Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
about
Structure of the human lung cytochrome P450 2A13Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient airIdentification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide eliminationSingle nucleotide polymorphisms (SNPs) are inherited from parents and they measure heritable eventsGene structure of CYP2C8 and extrahepatic distribution of the human CYP2CsInduction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell lineStructural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts.Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively.The inhaled glucocorticoid fluticasone propionate efficiently inactivates cytochrome P450 3A5, a predominant lung P450 enzyme.Lung cancer risk in workers exposed to poly(vinyl chloride) dust: a nested case-referent study.Pharmacogenetics of drug-metabolizing enzymes in US Hispanics.The Pesticide Metabolites Paraoxon and Malaoxon Induce Cellular Death by Different Mechanisms in Cultured Human Pulmonary Cells.The effect of trimethoprim on CYP2C8 mediated rosiglitazone metabolism in human liver microsomes and healthy subjects.Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.Role of GSTM1 in resistance to lung inflammation.Arylamine N-acetyltransferases: what we learn from genes and genomes.Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokersN-7-Alkyl-2'-Deoxyguanosine as surrogate biomarkers for N-nitrosamine exposure in human lung.Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung functionN-Acetyltransferase polymorphism and human cancer risk.Inhalative nanomedicine--opportunities and challenges.Differential suppression of the aryl hydrocarbon receptor nuclear translocator-dependent function by an aryl hydrocarbon receptor PAS-A-derived inhibitory molecule.Endothelial responses of the alveolar barrier in vitro in a dose-controlled exposure to diesel exhaust particulate matter.Cytochrome P450-mediated pulmonary metabolism of carcinogens: regulation and cross-talk in lung carcinogenesis.Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies.Insights on cytochrome p450 enzymes and inhibitors obtained through QSAR studies.The development of models for the evaluation of pulmonary drug disposition.Extrahepatic metabolism at the body's internal-external interfaces.Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.Halomethane-induced cytotoxicity and cell proliferation in human lung MRC-5 fibroblasts and NL20-TA epithelial cells.Impact of eugenol and isoeugenol on AhR translocation, target gene expression, and proliferation in human HaCaT keratinocytes.Impact of aryl hydrocarbon receptor (AhR) knockdown on cell cycle progression in human HaCaT keratinocytes.Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT).Antiproliferative effect of the Ginkgo biloba extract is associated with the enhancement of cytochrome P450 1B1 expression in estrogen receptor-negative breast cancer cellsOccupational exposure to aflatoxin (AFB₁) in poultry production.In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.Differential Regulation of CYP3A4 and CYP3A5 and its Implication in Drug Discovery.Extrahepatic Drug-Metabolizing Enzymes and Their Significance
P2860
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P2860
Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@ast
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@en
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@nl
type
label
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@ast
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@en
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@nl
prefLabel
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@ast
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@en
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@nl
P2093
P1476
Characterisation of xenobiotic ...... sa and peripheral lung tissues
@en
P2093
A M Pfeifer
C C Harris
E D Bowman
P G Shields
P Vautravers
P304
P356
10.1016/S0959-8049(98)00034-3
P407
P577
1998-05-01T00:00:00Z