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Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokersStructural diversity of eukaryotic membrane cytochrome p450sKey Residues Controlling Phenacetin Metabolism by Human Cytochrome P450 2A EnzymesInvestigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzymeStructural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpineNicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Binding and Access Channel in Human Cytochrome P450 2A6 and 2A13 EnzymesStructural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.X-ray structure of human aromatase reveals an androgen-specific active siteStructural differences between soluble and membrane bound cytochrome P450sp-dimethylaminocinnamaldehyde derivatization for colorimetric detection and HPLC-UV/vis-MS/MS identification of indolesNew insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS.Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compoundsInhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and mentholAn expression tag toolbox for microbial production of membrane bound plant cytochromes P450.Evaluation of inhibition selectivity for human cytochrome P450 2A enzymesCYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ionExpression of cytochrome P450 2A13 in human non-small cell lung cancer and its clinical significance.Thermodynamics of ligand binding to P450 2B4 and P450eryF studied by isothermal titration calorimetry.Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.Effect of CYP2A13 active site mutation N297A on metabolism of coumarin and tobacco-specific nitrosamines.Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.Conformational plasticity and structure/function relationships in cytochromes P450.Conformational diversity and ligand tunnels of mammalian cytochrome P450s.In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability.Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes.Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13Key residues controlling binding of diverse ligands to human cytochrome P450 2A enzymes.Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.Benzylmorpholine analogs as selective inhibitors of lung cytochrome P450 2A13 for the chemoprevention of lung cancer in tobacco users.Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea.Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2',5'-Tetrachlorobiphenyl.[Interference of homologous sequences on the SNP study of CYP2A13 gene].Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure of the human lung cytochrome P450 2A13
@ast
Structure of the human lung cytochrome P450 2A13
@en
Structure of the human lung cytochrome P450 2A13
@en-gb
Structure of the human lung cytochrome P450 2A13
@nl
type
label
Structure of the human lung cytochrome P450 2A13
@ast
Structure of the human lung cytochrome P450 2A13
@en
Structure of the human lung cytochrome P450 2A13
@en-gb
Structure of the human lung cytochrome P450 2A13
@nl
prefLabel
Structure of the human lung cytochrome P450 2A13
@ast
Structure of the human lung cytochrome P450 2A13
@en
Structure of the human lung cytochrome P450 2A13
@en-gb
Structure of the human lung cytochrome P450 2A13
@nl
P2093
P2860
P356
P1476
Structure of the human lung cytochrome P450 2A13
@en
P2093
Brian D Smith
C David Stout
Emily E Scott
Jason L Sanders
Patrick R Porubsky
P2860
P304
17306-17313
P356
10.1074/JBC.M702361200
P407
P577
2007-04-11T00:00:00Z