Phenotypic alteration of a human BK (hSlo) channel by hSlobeta subunit coexpression: changes in blocker sensitivity, activation/relaxation and inactivation kinetics, and protein kinase A modulation
about
Molecular mechanisms of large-conductance ca (2+) -activated potassium channel activation by ginseng gintoninA neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxinThe beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting statesStructural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channelFunction and regulation of large conductance Ca(2+)-activated K+ channel in vascular smooth muscle cellsFunctional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channelStimulatory action of internal protons on Slo1 BK channelsCompartmentalized beta subunit distribution determines characteristics and ethanol sensitivity of somatic, dendritic, and terminal large-conductance calcium-activated potassium channels in the rat central nervous systemFunction and mechanism of axonal targeting of voltage-sensitive potassium channels.Lysine-rich extracellular rings formed by hbeta2 subunits confer the outward rectification of BK channels.A BK (Slo1) channel journey from molecule to physiology.Molecular diversity and regulation of renal potassium channels.Distinct domains of the β1-subunit cytosolic N terminus control surface expression and functional properties of large-conductance calcium-activated potassium (BK) channelsIdentification and functional characterization of ankyrin-repeat family protein ANKRA as a protein interacting with BKCa channelInactivating BK channels in rat chromaffin cells may arise from heteromultimeric assembly of distinct inactivation-competent and noninactivating subunits.Large conductance voltage- and Ca2+-gated potassium (BK) channel β4 subunit influences sensitivity and tolerance to alcohol by altering its response to kinases.Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signalingOrientations and proximities of the extracellular ends of transmembrane helices S0 and S4 in open and closed BK potassium channels.Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension.The beta subunit of the high-conductance calcium-activated potassium channel contributes to the high-affinity receptor for charybdotoxin.Membrane-delimited inhibition of maxi-K channel activity by the intermediate conductance Ca2+-activated K channel.An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gatingKinetic structure of large-conductance Ca2+-activated K+ channels suggests that the gating includes transitions through intermediate or secondary states. A mechanism for flickers.Differential effects of beta 1 and beta 2 subunits on BK channel activity.Allosteric gating of a large conductance Ca-activated K+ channel.Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channelsGating kinetics of single large-conductance Ca2+-activated K+ channels in high Ca2+ suggest a two-tiered allosteric gating mechanismFunctional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism.Role of the beta1 subunit in large-conductance Ca(2+)-activated K(+) channel gating energetics. Mechanisms of enhanced Ca(2+) sensitivity.An unexpected journey: conceptual evolution of mechanoregulated potassium transport in the distal nephron.Diabetes downregulates large-conductance Ca2+-activated potassium beta 1 channel subunit in retinal arteriolar smooth muscleIdentification and characterization of Ca2+-activated K+ channels in granulosa cells of the human ovaryβ1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channelRegulation of colonic apical potassium (BK) channels by cAMP and somatostatin.Mechanoregulation of BK channel activity in the mammalian cortical collecting duct: role of protein kinases A and C.Conopeptide Vt3.1 preferentially inhibits BK potassium channels containing β4 subunits via electrostatic interactions.Targeting BK (big potassium) channels in epilepsy.Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunitsCa2+-activated K channels in parotid acinar cells: The functional basis for the hyperpolarized activation of BK channels.BKCa currents are enriched in a subpopulation of adult rat cutaneous nociceptive dorsal root ganglion neurons.
P2860
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P2860
Phenotypic alteration of a human BK (hSlo) channel by hSlobeta subunit coexpression: changes in blocker sensitivity, activation/relaxation and inactivation kinetics, and protein kinase A modulation
description
1996 nî lūn-bûn
@nan
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@ast
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@en
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@nl
type
label
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@ast
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@en
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@nl
prefLabel
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@ast
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@en
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@nl
P2093
P1476
Phenotypic alteration of a hum ...... nd protein kinase A modulation
@en
P2093
C G Boissard
D J Post-Munson
J T Lum-Ragan
J T Trojnacki
S I Dworetzky
V K Gribkoff
P304
P356
10.1523/JNEUROSCI.16-15-04543.1996
P407
P577
1996-08-01T00:00:00Z