about
An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machineEnglerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethalityMolecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysisDiscovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjectsTargeted drugs in small-cell lung cancerOther targeted drugs in melanomaHeat shock protein 90 targeting therapy: state of the art and future perspectiveHSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative NeoplasmsHsp90: A New Player in DNA Repair?Treating patients with ALK-positive non-small cell lung cancer: latest evidence and management strategyNew molecular targets in mantle cell lymphomaThe G protein α chaperone Ric-8 as a potential therapeutic targetExpanding proteostasis by membrane trafficking networksThe 'active life' of Hsp90 complexesQuality control and fate determination of Hsp90 client proteinsHeat shock proteins at the crossroads between cancer and Alzheimer's diseaseMechanisms of protein-folding diseases at a glanceProtein homeostasis as a therapeutic target for diseases of protein conformationChemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosisProtein homeostasis at the plasma membraneAdvances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancersTargeting Hsp90 in urothelial carcinomaChaperone machines for protein folding, unfolding and disaggregationHeat shock transcription factor 1 as a therapeutic target in neurodegenerative diseasesModulation of the maladaptive stress response to manage diseases of protein foldingHSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivoCorresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulationsThe hexameric structures of human heat shock protein 90Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90Synthesis of benzoquinone ansamycin-inspired macrocyclic lactams from shikimic acidSynthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation.Anti-Hsp90 therapy in autoimmune and inflammatory diseases: a review of preclinical studiesAn integrated view of cisplatin-induced nephrotoxicity and ototoxicityNKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple MyelomaKDM1 class flavin-dependent protein lysine demethylasesDistinct roles of molecular chaperones HSP90α and HSP90β in the biogenesis of KCNQ4 channelsApproaches for defining the Hsp90-dependent proteome.Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair fociAmplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeting the dynamic HSP90 complex in cancer
@ast
Targeting the dynamic HSP90 complex in cancer
@en
Targeting the dynamic HSP90 complex in cancer
@nl
type
label
Targeting the dynamic HSP90 complex in cancer
@ast
Targeting the dynamic HSP90 complex in cancer
@en
Targeting the dynamic HSP90 complex in cancer
@nl
prefLabel
Targeting the dynamic HSP90 complex in cancer
@ast
Targeting the dynamic HSP90 complex in cancer
@en
Targeting the dynamic HSP90 complex in cancer
@nl
P2093
P3181
P356
P1476
Targeting the dynamic HSP90 complex in cancer
@en
P2093
Jane Trepel
Len Neckers
Mehdi Mollapour
P2888
P304
P3181
P356
10.1038/NRC2887
P407
P577
2010-08-01T00:00:00Z
P6179
1006993157