Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites
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Modeling of the spatial structure of eukaryotic ornithine decarboxylasesStructural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive EvolutionIdentification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both L-ornithine and L-lysineCharacterization of the Entamoeba histolytica ornithine decarboxylase-like enzymePoisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparumBiochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolyticaUntargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma bruceiMultiple active conformers of mouse ornithine decarboxylasePolyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilitiesLegionella pneumophila requires polyamines for optimal intracellular growth.Current concepts in colorectal cancer preventionLeishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs.Cloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain.Fluorinated Sterols Are Suicide Inhibitors of Ergosterol Biosynthesis and Growth in Trypanosoma brucei.Multifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor.Molecular cloning and characterization of ornithine decarboxylase cDNA of the nematode Panagrellus redivivusCloning and sequence analysis of the meso-diaminopimelate decarboxylase gene from Bacillus methanolicus MGA3 and comparison to other decarboxylase genes.Panagrellus redivivus ornithine decarboxylase: structure of the gene, expression in Escherichia coli and characterization of the recombinant protein.Crenarchaeal arginine decarboxylase evolved from an S-adenosylmethionine decarboxylase enzyme.Critical factors determining dimerization of human antizyme inhibitor.The C-terminus of rat L-histidine decarboxylase specifically inhibits enzymic activity and disrupts pyridoxal phosphate-dependent interactions with L-histidine substrate analoguesPrivileged Electrophile Sensors: A Resource for Covalent Drug Development.Control of filament formation in Candida albicans by polyamine levels.Gene cloning and molecular characterization of lysine decarboxylase from Selenomonas ruminantium delineate its evolutionary relationship to ornithine decarboxylases from eukaryotes.Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion.L-allo-threonine aldolase from Aeromonas jandaei DK-39: gene cloning, nucleotide sequencing, and identification of the pyridoxal 5'-phosphate-binding lysine residue by site-directed mutagenesis.Proteoglycan involvement in polyamine uptake.Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical AdvantagesOverexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy.Examination of the new alpha-(2'Z-fluoro)vinyl trigger with lysine decarboxylase: the absolute stereochemistry dictates the reaction course.Structural motifs for pyridoxal-5'-phosphate binding in decarboxylases: an analysis based on the crystal structure of the Lactobacillus 30a ornithine decarboxylase.Molecular cloning and functional identification of a plant ornithine decarboxylase cDNA.Dual Regulatory Role of Polyamines in Adipogenesis.Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation.Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.Synthesis and Deployment of an Elusive Fluorovinyl Cation Equivalent: Access to Quaternary α-(1'-Fluoro)vinyl Amino Acids as Potential PLP Enzyme Inactivators.Evaluation of Polyamine Transport Inhibitors in a Drosophila Epithelial Model Suggests the Existence of Multiple Transport Systems.Free α-Oxiranyl Amino Acids.Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives
P2860
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P2860
Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Mechanism of the irreversible ...... tor and coenzyme binding sites
@ast
Mechanism of the irreversible ...... tor and coenzyme binding sites
@en
Mechanism of the irreversible ...... tor and coenzyme binding sites
@nl
type
label
Mechanism of the irreversible ...... tor and coenzyme binding sites
@ast
Mechanism of the irreversible ...... tor and coenzyme binding sites
@en
Mechanism of the irreversible ...... tor and coenzyme binding sites
@nl
prefLabel
Mechanism of the irreversible ...... tor and coenzyme binding sites
@ast
Mechanism of the irreversible ...... tor and coenzyme binding sites
@en
Mechanism of the irreversible ...... tor and coenzyme binding sites
@nl
P2093
P1476
Mechanism of the irreversible ...... tor and coenzyme binding sites
@en
P2093
P407
P577
1992-01-05T00:00:00Z