Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling
about
Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho familyRole of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migrationSH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinaseHuman GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domainsAssociation of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulinAnalysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3Kinase activation through dimerization by human SH2-BRole for the adaptor protein Grb10 in the activation of AktThe adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase CzetaGrb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesisIdentification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signalingTwo adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinaseThe Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptorRegulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteinsStructural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificityAssociation of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partnerIdentification of Grb10 as a direct substrate for members of the Src tyrosine kinase familyDirect binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkAAssociation of focal adhesion kinase with Grb7 and its role in cell migrationEvidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent mannerCloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gammaInteraction of the Grb10 adapter protein with the Raf1 and MEK1 kinasesGrb10/GrbIR as an in vivo substrate of Tec tyrosine kinaseInteraction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activationTwo novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signalingmGrb10 interacts with Nedd4Identification of the rat adapter Grb14 as an inhibitor of insulin actionsIdentification of the APS protein as a novel insulin receptor substrateThe adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblastsPost-natal imprinting: evidence from marsupialsCrystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analogDisruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate.Inhibition of hGrb10 binding to the insulin receptor by functional domain-mediated oligomerization.Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.Imprinting of human GRB10 and its mutations in two patients with Russell-Silver syndrome.Duplication of 7p11.2-p13, including GRB10, in Silver-Russell syndromeSilver-Russell syndrome: a dissection of the genetic aetiology and candidate chromosomal regions.
P2860
Q22011215-706B34ED-3136-4C4A-BA74-C66606A601FAQ22254608-4C409C29-96DC-4A2C-ADBB-0140AEBED073Q24314668-B528AA3D-18C5-4C82-8166-06B82497EFA3Q24315001-72609C20-E40E-47A3-8136-92833280D9CFQ24318310-928F2910-CDF0-48E1-9E1A-AF43A6923591Q24319261-A2887A5C-BB56-43F6-A0F2-18CF9D874EC8Q24519086-CEA7C072-8228-4BF7-8552-86376BC39374Q24537512-9E4D01C3-E6FC-44C7-ABEC-12E0DCBF5C5AQ24540143-AD26411A-F5A3-4EF0-AC89-A8657746E96AQ24554440-ADB82B19-7196-4F55-BB17-96AF2E35E5F7Q24644273-3EB69E72-8BFD-4596-8044-0272DF7BF3B3Q24654769-6EBCBBEA-6055-49F4-BCC1-66F72DAB46B2Q24682781-F6751A84-B67E-48D2-BF69-79C4EDE586D4Q26849720-29B3428B-5859-4E1F-BC65-9A4542CA975AQ27640366-64B03161-9557-49D2-845D-A87D5B8BDC5CQ28138292-B47AB546-2A5B-4283-A18C-C1C7522BE4BEQ28139366-E65A0C46-B308-4D3E-B9F7-A051BCBE43DAQ28140629-4E269EF8-2576-4442-B984-F4E6E1DA8B7AQ28142084-3BBBF04A-874A-466F-BDFA-7A55BD03A54EQ28143997-F267DB26-B862-4740-8467-434127503730Q28199355-26C43E95-8188-415A-A1E2-0C983B1C6D2BQ28235588-BAADCAA6-DE96-4B15-82A9-51363F5EB42EQ28253807-54B6537B-AE91-41C9-B486-30D8C9D37FB2Q28268392-08B81E21-52F4-4658-BE19-78071A6FD08FQ28283759-E4D9E52F-F397-45D5-B040-CA7DE2B361FCQ28307097-46D5D246-EF33-472B-BEEC-1EED99B1E06AQ28505191-8B6F4E60-88EA-4A17-A927-0C1A8A7FCE99Q28508597-1A640D73-A876-4795-AC4F-5086A3179FC9Q28565588-4D202331-FE79-43D3-BCD9-E819A5DD8339Q28587602-42B4782C-FA26-4731-90AD-8D0747CC980EQ28591965-3A769033-6F9D-458D-8D17-0D23214535CFQ28655490-61E555A3-DFF5-4F6F-8A0D-3A738336376AQ29616450-2FB682D8-18E8-4179-B18A-105058671D18Q30176313-C1468801-10CE-445A-BDA6-559223AC8AA5Q32058435-CFADD45F-3258-4998-A523-425FEC5A1ABAQ33780305-AFD205FB-4BAD-42CB-A1C9-436CCF3AC6D5Q34103542-D4E3CA67-7EBE-440D-8FE1-7FA324715DCDQ34142141-A7497888-DE70-4D93-B11F-C335E200AD57Q34146198-413E657D-7885-4F75-8571-9D4255375317Q34465575-C0BB3942-1F24-4315-8CBE-59E5A45C6F88
P2860
Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling
description
1996 nî lūn-bûn
@nan
1996 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@ast
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@en
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@nl
type
label
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@ast
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@en
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@nl
prefLabel
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@ast
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@en
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@nl
P2093
P356
P1476
Interaction of a GRB-IR splice ...... a role in mitogenic signaling
@en
P2093
T A Gustafson
T J O'Neill
T S Pillay
P304
P356
10.1074/JBC.271.37.22506
P407
P577
1996-09-13T00:00:00Z