Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.
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Spinal muscular atrophyModeling spinal muscular atrophy in DrosophilaDcpS as a therapeutic target for spinal muscular atrophy.The many roles of histone deacetylases in development and physiology: implications for disease and therapyDelivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibitionHistone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibersMolecular Mechanisms of Neurodegeneration in Spinal Muscular AtrophySpinal muscular atrophy: from gene discovery to clinical trialsHistone deacetylase inhibitors as potential treatment for spinal muscular atrophySpinal muscular atrophy: development and implementation of potential treatmentsApplicability of histone deacetylase inhibition for the treatment of spinal muscular atrophySplicing therapy for neuromuscular diseaseHigh expression level of Tra2-β1 is responsible for increased SMN2 exon 7 inclusion in the testis of SMA miceMutations in TRPV4 cause Charcot-Marie-Tooth disease type 2CHistone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regenerationThe promise and perils of HDAC inhibitors in neurodegenerationProlactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway.Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic responseSAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophySustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutritionArrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice.Epigenetics in the nervous systemIdentification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screeningHistone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and effluxSepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscleYeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseasesUtility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analysesThe Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and menTranslational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivoEffects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophyCNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy.Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.Sodium vanadate combined with L-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy.The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models.Protective effects of butyrate-based compounds on a mouse model for spinal muscular atrophy.Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPsThe effect of diet on the protective action of D156844 observed in spinal muscular atrophy mice.Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophyMouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not late
P2860
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P2860
Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Trichostatin A increases SMN e ...... del of spinal muscular atrophy
@nl
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@ast
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@en
type
label
Trichostatin A increases SMN e ...... del of spinal muscular atrophy
@nl
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@ast
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@en
prefLabel
Trichostatin A increases SMN e ...... del of spinal muscular atrophy
@nl
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@ast
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@en
P2093
P2860
P3181
P356
P1476
Trichostatin A increases SMN e ...... el of spinal muscular atrophy.
@en
P2093
Addis A Taye
Amy M Avila
Barrington G Burnett
Charlotte J Sumner
Francesca Gabanella
Kenneth H Fischbeck
Livio Pellizzoni
Melanie A Knight
Nicholas A Di Prospero
Parvana Hartenstein
P2860
P304
P3181
P356
10.1172/JCI29562
P407
P577
2007-02-22T00:00:00Z