Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux
about
Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells.Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrinMetabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with TemozolomideInhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver.Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis.Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis.Altered Cholesterol Intracellular Trafficking and the Development of Pathological Hallmarks of Sporadic AD.Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1).Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat.Epigenetic therapies - a new direction in clinical medicine.
P2860
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P2860
Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@ast
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@nl
type
label
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@ast
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@nl
prefLabel
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@ast
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@nl
P2860
P50
P1433
P1476
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
P2093
Cecília M P Rodrigues
P2860
P304
P356
10.1371/JOURNAL.PONE.0053394
P407
P577
2013-01-01T00:00:00Z