Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
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Exosomes: The Link between GPCR Activation and Metastatic Potential?Current State of Animal (Mouse) Modeling in Melanoma ResearchPathways and therapeutic targets in melanomaBiology, Therapy and Implications of Tumor Exosomes in the Progression of MelanomaImpaired gp100-Specific CD8(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma ModelDiscovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancerA novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptorsN-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats.Metabotropic glutamate receptors: from the workbench to the bedside.Metabotropic glutamate receptors (mGlus) and cellular transformation.Serum glutamate levels correlate with Gleason score and glutamate blockade decreases proliferation, migration, and invasion and induces apoptosis in prostate cancer cellsMetabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).A phase 0 trial of riluzole in patients with resectable stage III and IV melanomaIntegrated analysis of mutations, miRNA and mRNA expression in glioblastoma.Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformationRecent advances in drug repositioning for the discovery of new anticancer drugsNetwork-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma.Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancerGRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma(1)H NMR Metabolomics Study of Metastatic Melanoma in C57BL/6J Mouse Spleen.Riluzole mediates anti-tumor properties in breast cancer cells independent of metabotropic glutamate receptor-1.Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanomaHypoxia-inducible factors enhance glutamate signaling in cancer cellsComprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profilingMetabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain.Metabotropic glutamate receptor-1 as a novel target for the antiangiogenic treatment of breast cancerExpression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice.Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism.Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation.Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective.The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.Metastatic Melanoma Induced Metabolic Changes in C57BL/6J Mouse Stomach Measured by 1H NMR Spectroscopy.Effect of (S)-3,5-DHPG on microRNA expression in mouse brain.Delving into somatic variation in sporadic melanoma.Molecular pathways: dysregulated glutamatergic signaling pathways in cancerOsteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole.
P2860
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P2860
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@ast
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@en
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@nl
type
label
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@ast
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@en
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@nl
prefLabel
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@ast
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@en
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@nl
P2093
P3181
P1433
P1476
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
@en
P2093
Brian A Wall
Hwa Jin Lee
James S Goydos
Jin Namkoong
Seung-Shick Shin
Suzie Chen
Yarí E Marín
P304
P3181
P356
10.1158/0008-5472.CAN-06-3665
P407
P577
2007-03-01T00:00:00Z