The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation - Wikidata - wikimedia - TriplyDB

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

http://www.wikidata.org/entity/Q28291406

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Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2)The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK.Regulation and function of AMPK in physiology and diseases Energy metabolism in neurodevelopment and medulloblastoma Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases Translational progress on tumor biomarkers Oncogenes strike a balance between cellular growth and homeostasis Endocrine regulation of fetal skeletal muscle growth: impact on future metabolic health Folliculin regulates ampk-dependent autophagy and metabolic stress survival Structure of the C-Terminal Helical Repeat Domain of Eukaryotic Elongation Factor 2 Kinase The molecular mechanism of eukaryotic elongation factor 2 kinase activation Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?Detecting translational regulation by change point analysis of ribosome profiling data sets The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells Enhanced arginine methylation of programmed cell death 4 protein during nutrient deprivation promotes tumor cell viability.New frontiers in translational control of the cancer genome Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling eEF2K--a new target in breast cancers with combined inactivation of p53 and PTEN Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K High-throughput screens for eEF-2 kinase.Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes Mechanism of cytoplasmic mRNA translation.RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer Protein synthesis during cellular quiescence is inhibited by phosphorylation of a translational elongation factor.Phosphatase control of 4E-BP1 phosphorylation state is central for glycolytic regulation of retinal protein synthesis.Pausing on Polyribosomes: Make Way for Elongation in Translational Control A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors.Gα12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction Germline quality control: eEF2K stands guard to eliminate defective oocytes Stress-induced inhibition of translation independently of eIF2α phosphorylation.AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) α-kinase domain apoenzyme reveals a novel autoinhibited conformation.IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation.FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells.

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The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

http://www.wikidata.org/entity/Q28291406

description

2013 nî lūn-bûn

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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013 թվականի մայիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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name

The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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type

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The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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prefLabel

The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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The eEF2 kinase confers resist ...... locking translation elongation

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Abigail-Rachele F Mateo

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Adi Barokas

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Adrian Dubuc

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Amal El-Naggar

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Amy Li

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Andrey Korshunov

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Barak Rotblat

http://www.w3.org/2001/XMLSchema#string

Bin Yu

http://www.w3.org/2001/XMLSchema#string

Brian Kwok

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Cristina E Tognon

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P2860

The genetics of Caenorhabditis elegans

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

mTOR: from growth signal integration to cancer, diabetes and ageing

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

Tumours with PI3K activation are resistant to dietary restriction

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Why are tumour blood vessels abnormal and why is it important to know?

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

TSC2 mediates cellular energy response to control cell growth and survival

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

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153

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Christopher G. Proud

Stefan M Pfister

Brandon Faubert

Christopher A Ahern

Olivier Delattre

Syam Prakash Somasekharan

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2013-05-01T00:00:00Z

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