Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin
about
Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localizationLeupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cellsSmad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcriptionPTP-1B is an essential positive regulator of platelet integrin signalingInteraction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix.Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinasePaxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.LIM domains target actin regulators paxillin and zyxin to sites of stress fiber strainPaxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish HeartPxl1p, a paxillin-like protein in Saccharomyces cerevisiae, may coordinate Cdc42p and Rho1p functions during polarized growth.Hic-5 is required for fetal gene expression and cytoskeletal organization of neonatal cardiac myocytesInvolvement of Hic-5 in platelet activation: integrin alphaIIbbeta3-dependent tyrosine phosphorylation and association with proline-rich tyrosine kinase 2Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoAMyosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signalingMinimal features of paxillin that are required for the tyrosine phosphorylation of focal adhesion kinaseTransformation by bovine papillomavirus type 1 E6 requires paxillin.Two-color photoactivatable probe for selective tracking of proteins and cells.HSP27 regulates fibroblast adhesion, motility, and matrix contraction.Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampiRegulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton.Epithelial Hic-5/ARA55 expression contributes to prostate tumorigenesis and castrate responsiveness.Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.Hic-5, an adaptor-like nuclear receptor coactivator.Paxillin and phospholipase D interact to regulate actin-based processes in Dictyostelium discoideum.Amino acid transporters: roles in amino acid sensing and signalling in animal cells.Hic-5 Mediates TGFβ-Induced Adhesion in Vascular Smooth Muscle Cells by a Nox4-Dependent Mechanism.Transforming growth factor-β1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin proteinHic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition.Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.Cytomegalovirus destruction of focal adhesions revealed in a high-throughput Western blot analysis of cellular protein expression.Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork CellsGIT1 utilizes a focal adhesion targeting-homology domain to bind paxillinTransforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/SrcHic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase.Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulationExpression of phosphorylated heat shock protein 27 during corneal epithelial wound healing.
P2860
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P2860
Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Characterization of a focal ad ...... tensive homology with paxillin
@ast
Characterization of a focal ad ...... tensive homology with paxillin
@en
Characterization of a focal ad ...... tensive homology with paxillin
@nl
type
label
Characterization of a focal ad ...... tensive homology with paxillin
@ast
Characterization of a focal ad ...... tensive homology with paxillin
@en
Characterization of a focal ad ...... tensive homology with paxillin
@nl
prefLabel
Characterization of a focal ad ...... tensive homology with paxillin
@ast
Characterization of a focal ad ...... tensive homology with paxillin
@en
Characterization of a focal ad ...... tensive homology with paxillin
@nl
P2093
P1476
Characterization of a focal ad ...... tensive homology with paxillin
@en
P2093
P304
P407
P478
112 ( Pt 2)
P577
1999-01-01T00:00:00Z