TLR8 deficiency leads to autoimmunity in mice - Wikidata - wikimedia - TriplyDB

TLR8 deficiency leads to autoimmunity in mice

TLR8 deficiency leads to autoimmunity in mice

http://www.wikidata.org/entity/Q28292240

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Innate immune sensing of DNA viruses Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic intervention Intracellular nucleic acid sensors and autoimmunity Phagosomal TLR signaling upon Borrelia burgdorferi infection TLRs and interferons: a central paradigm in autoimmunity TLR8: the forgotten relative revindicated Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells Molecular cloning and functional characterization of murine toll‑like receptor 8 Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus.The therapeutic potential of Toll-like receptor 7 stimulation in asthma.Spontaneous activation of RNA-sensing pathways in autoimmune disease.Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivation.Humanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.Placental Toll-like receptor 3 and Toll-like receptor 7/8 activation contributes to preeclampsia in humans and mice.Liver-inherent immune system: its role in blood-stage malaria.Role of Toll-like receptor 13 in innate immune recognition of group B streptococci.1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivo Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation.The expression of Toll-like receptor 8 and its relationship with VEGF and Bcl-2 in cervical cancer.TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Resurrection of endogenous retroviruses in antibody-deficient mice B-cell selection and the development of autoantibodies.Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9.Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response.Impaired toll-like receptor 8 signaling in multiple sclerosis.Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells.Toll-like receptor 7 rapidly relaxes human airways.Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes RNA recognition by human TLR8 can lead to autoimmune inflammation.Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population.TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice TLR7 Deficiency Leads to TLR8 Compensative Regulation of Immune Response against JEV in Mice Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo.Toll-like receptor driven B cell activation in the induction of systemic autoimmunity.

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P2860

TLR8 deficiency leads to autoimmunity in mice

http://www.wikidata.org/entity/Q28292240

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

name

TLR8 deficiency leads to autoimmunity in mice

@ast

TLR8 deficiency leads to autoimmunity in mice

@en

TLR8 deficiency leads to autoimmunity in mice

@nl

type

label

TLR8 deficiency leads to autoimmunity in mice

@ast

TLR8 deficiency leads to autoimmunity in mice

@en

TLR8 deficiency leads to autoimmunity in mice

@nl

prefLabel

TLR8 deficiency leads to autoimmunity in mice

@ast

TLR8 deficiency leads to autoimmunity in mice

@en

TLR8 deficiency leads to autoimmunity in mice

@nl

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P1433

Journal of Clinical Investigation

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TLR8 deficiency leads to autoimmunity in mice

@en

P2093

David M Valenzuela

http://www.w3.org/2001/XMLSchema#string

George D Yancopoulos

http://www.w3.org/2001/XMLSchema#string

Olivier Demaria

http://www.w3.org/2001/XMLSchema#string

Philippe P Pagni

http://www.w3.org/2001/XMLSchema#string

Richard A Flavell

http://www.w3.org/2001/XMLSchema#string

Stephanie Traub

http://www.w3.org/2001/XMLSchema#string

P2860

Discrimination of bacterial lipoproteins by Toll-like receptor 6

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Recognition of single-stranded RNA viruses by Toll-like receptor 7

Progenitors for Ly-1 B cells are distinct from progenitors for other B cells

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

B1 cells: similarities and differences with other B cell subsets

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

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10.1172/JCI42081

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P433

10

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P478

120

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Andrew J Murphy

Lena Alexopoulou

Aude De Gassart

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2010-10-01T00:00:00Z

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P698

20811154

http://www.w3.org/2001/XMLSchema#string

P921

Toll-like receptor

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2947223

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