The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons
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Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesImplementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.Role of histamine and its receptors in cerebral ischemiaInhibition of histamine receptor 3 suppresses glioblastoma tumor growth, invasion, and epithelial-to-mesenchymal transition.Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats.Effects of the H(3) antagonist, thioperamide, on behavioral alterations induced by systemic MK-801 administration in rats.Histamine H3 and H4 receptors as novel drug targets.Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms.Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives.Procognitive properties of drugs with single and multitargeting H3 receptor antagonist activities.Adamantane-Isothiourea Hybrid Derivatives: Synthesis, Characterization, In Vitro Antimicrobial, and In Vivo Hypoglycemic Activities.The Histamine H3 Receptor: Structure, Pharmacology, and Function.H3 receptor antagonism enhances NCAM PSA-mediated plasticity and improves memory consolidation in odor discrimination and delayed match-to-position paradigms.Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists.Thioperamide treats neonatal hypoxic-ischemic encephalopathy by postsynaptic H1 receptors.Predicting targets of compounds against neurological diseases using cheminformatic methodology.Histamine H3 Inverse Agonist BF 2649 or Antagonist with Partial H4 Agonist Activity Clobenpropit Reduces Amyloid Beta Peptide-Induced Brain Pathology in Alzheimer's Disease.(R)-alpha-methylhistamine suppresses inhibitory neurotransmission in hippocampal CA1 pyramidal neurons counteracting propofol-induced amnesia in rats.Superficial Layer-Specific Histaminergic Modulation of Medial Entorhinal Cortex Required for Spatial Learning.Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: lack of histaminergic mechanisms.
P2860
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P2860
The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
@yue
name
The histamine H3 receptor anta ...... y in cultured cortical neurons
@ast
The histamine H3 receptor anta ...... y in cultured cortical neurons
@en
The histamine H3 receptor anta ...... y in cultured cortical neurons
@nl
type
label
The histamine H3 receptor anta ...... y in cultured cortical neurons
@ast
The histamine H3 receptor anta ...... y in cultured cortical neurons
@en
The histamine H3 receptor anta ...... y in cultured cortical neurons
@nl
prefLabel
The histamine H3 receptor anta ...... y in cultured cortical neurons
@ast
The histamine H3 receptor anta ...... y in cultured cortical neurons
@en
The histamine H3 receptor anta ...... y in cultured cortical neurons
@nl
P2093
P3181
P1476
The histamine H3 receptor anta ...... y in cultured cortical neurons
@en
P2093
Henk Timmerman
Zhong Chen
Zhongmiao Zhang
P304
P3181
P356
10.1016/J.EJPHAR.2007.01.069
P407
P50
P577
2007-02-08T00:00:00Z