Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
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International Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsGlutamate receptor ion channels: structure, regulation, and functionQuinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists.Control of assembly and function of glutamate receptors by the amino-terminal domain.Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulatorsMPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.Molecular pharmacology of human NMDA receptorsAn Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors.Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.NMDA receptor antagonism with novel indolyl, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy.Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptorsAllosteric modulators for the treatment of schizophrenia: targeting glutamatergic networksIon channel drug discovery: challenges and future directions.A Molecular Approach to Epilepsy Management: from Current Therapeutic Methods to Preconditioning Efforts.Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators.Contribution of NRG1 Gene Polymorphisms in Temporal Lobe Epilepsy.A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine.The bioactive protein-ligand conformation of GluN2C-selective positive allosteric modulators bound to the NMDA receptor.A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons.
P2860
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P2860
Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Implementation of a fluorescen ...... spartate receptor antagonists.
@ast
Implementation of a fluorescen ...... spartate receptor antagonists.
@en
Implementation of a fluorescen ...... spartate receptor antagonists.
@nl
type
label
Implementation of a fluorescen ...... spartate receptor antagonists.
@ast
Implementation of a fluorescen ...... spartate receptor antagonists.
@en
Implementation of a fluorescen ...... spartate receptor antagonists.
@nl
prefLabel
Implementation of a fluorescen ...... spartate receptor antagonists.
@ast
Implementation of a fluorescen ...... spartate receptor antagonists.
@en
Implementation of a fluorescen ...... spartate receptor antagonists.
@nl
P2093
P2860
P50
P356
P1476
Implementation of a fluorescen ...... spartate receptor antagonists.
@en
P2093
Anna G Orr
Hongjie Yuan
Iestyn Lewis
James P Snyder
Katie M Vance
Kimberly M Vellano
Natalie L Kurtkaya
Praseeda Mullasseril
P2860
P304
P356
10.1124/JPET.110.166256
P407
P577
2010-03-02T00:00:00Z