Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development

Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development

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http://www.wikidata.org/entity/Q28292810

Q28292810

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Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1 Expression of Groucho/TLE proteins during pancreas development Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation Antagonistic effects of Grg6 and Groucho/TLE on the transcription repression activity of brain factor 1/FoxG1 and cortical neuron differentiation.A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development Groucho oligomerization is required for repression in vivo Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth Cellular corepressor TLE2 inhibits replication-and-transcription- activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus.Cofactor-activated phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1.Functional dissection of the global repressor Tup1 in yeast: dominant role of the C-terminal repression domain.The germ cell nuclear proteins hnRNP G-T and RBMY activate a testis-specific exon.Arbiter of differentiation and death: Notch signaling meets apoptosis.Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling.A role for cell cycle-regulated phosphorylation in Groucho-mediated transcriptional repression.AES/GRG5: more than just a dominant-negative TLE/GRG family member Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression.Inhibition of cortical neuron differentiation by Groucho/TLE1 requires interaction with WRPW, but not Eh1, repressor peptides.Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation.Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.Transcriptional repression by Tup1-Ssn6.Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway.Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter.Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE)The homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expression during kidney development.Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.O-GlcNAc transferase is critical for transducin-like enhancer of split (TLE)-mediated repression of canonical Wnt signaling.A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome.The Groucho/Transducin-like enhancer of split protein family in animal development.The Groucho/TLE/Grg family of transcriptional co-repressors.Hes1: the maestro in neurogenesis.Negative regulation of CD4 gene expression by a HES-1-c-Myb complex.The E2A-HLF oncoprotein activates Groucho-related genes and suppresses Runx1.FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation.

P2860

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P2860

Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development

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http://www.wikidata.org/entity/Q28292810

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1998 nî lūn-bûn

@nan

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu