about
Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brainStructural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1Metabolic profiling of cholesterol and sex steroid hormones to monitor urological diseasesVariations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamilySpatial distribution of the pathways of cholesterol homeostasis in human retinaNeurobehavioral abnormalities in a brain-specific NADPH-cytochrome P450 reductase knockout mouse modelTherapeutic approaches to drug targets in atherosclerosis.Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells.Studies of membrane topology of mitochondrial cholesterol hydroxylases CYPs 27A1 and 11A1High fat diet modulates Trypanosoma cruzi infection associated myocarditis.Identification and analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in cynomolgus macaquesCytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1.Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies.Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.Ligands of Therapeutic Utility for the Liver X Receptors.Metabolic host responses to infection by intracellular bacterial pathogensAntioxidant Supplements Improve Profiles of Hepatic Oxysterols and Plasma Lipids in Butter-fed HamstersCholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb.Steroid and protein ligand binding to cytochrome P450 46A1 as assessed by hydrogen-deuterium exchange and mass spectrometry.High-temperature GC-MS-based serum cholesterol signatures may reveal sex differences in vasospastic anginaModified SJH alleviates FFAs-induced hepatic steatosis through leptin signaling pathways.Involvement of free radicals and oxidative stress in NAFLD/NASH.Cytochrome P450 and myocardial ischemia: potential pharmacological implication for cardioprotection.Regioselective hydroxylation of steroid hormones by human cytochromes P450.Dual effect of docosahexaenoic acid (attenuation or amplification) on C22:0-, C24:0-, and C26:0-induced mitochondrial dysfunctions and oxidative stress on human neuronal SK-N-BE cells.Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.Cholesterol hydroperoxides as substrates for cholesterol-metabolizing cytochrome P450 enzymes and alternative sources of 25-hydroxycholesterol and other oxysterols.Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatmentsDoes the long plasma half-life of 4beta-hydroxycholesterol impact its utility as a cytochrome P450 3A (CYP3A) metric?Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS.Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium.Development of a novel method for quantification of sterols and oxysterols by UPLC-ESI-HRMS: application to a neuroinflammation rat model.Amyloid Beta Peptides Affect Pregnenolone and Pregnenolone Sulfate Levels in PC-12 and SH-SY5Y Cells Depending on Cholesterol.Interactions between CYP7A1 A-204C and ABCG8 C1199A polymorphisms on lipid lowering with atorvastatin.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cholesterol-metabolizing cytochromes P450
@ast
Cholesterol-metabolizing cytochromes P450
@en
Cholesterol-metabolizing cytochromes P450
@nl
type
label
Cholesterol-metabolizing cytochromes P450
@ast
Cholesterol-metabolizing cytochromes P450
@en
Cholesterol-metabolizing cytochromes P450
@nl
prefLabel
Cholesterol-metabolizing cytochromes P450
@ast
Cholesterol-metabolizing cytochromes P450
@en
Cholesterol-metabolizing cytochromes P450
@nl
P3181
P356
P1476
Cholesterol-metabolizing cytochromes P450
@en
P2093
Irina A Pikuleva
P304
P3181
P356
10.1124/DMD.105.008789
P407
P577
2006-01-24T00:00:00Z