Etoposide: four decades of development of a topoisomerase II inhibitor
about
Characterization of fortilin, a novel antiapoptotic proteinCellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpointsHsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cellsAMF1 (GPS2) modulates p53 transactivation(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesBioflavonoids as poisons of human topoisomerase II alpha and II betaDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementCollision of Trapped Topoisomerase 2 with Transcription and Replication: Generation and Repair of DNA Double-Strand Breaks with 5' AdductsThe Role of the Neuroprotective Factor Npas4 in Cerebral IschemiaMolecular mechanisms of etoposideEvolving concepts in cancer therapy through targeting sphingolipid metabolismRecent progress on C-4-modified podophyllotoxin analogs as potent antitumor agentsDiscovery of new anticancer agents from higher plantsMechanism of repair of 5′-topoisomerase II–DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosisConsensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cellsDifferential gene and microRNA expression between etoposide resistant and etoposide sensitive MCF7 breast cancer cell linesFunctional investigation of NCI-H460-inducible myofibroblasts on the chemoresistance to VP-16 with a microfluidic 3D co-culture deviceReplication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposideMultiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheresAppraisals of Bangladeshi Medicinal Plants Used by Folk Medicine Practitioners in the Prevention and Management of Malignant Neoplastic DiseasesMechanisms and Consequences of Double-Strand DNA Break Formation in ChromatinNovel linear and step-gradient counter-current chromatography for bio-guided isolation and purification of cytotoxic podophyllotoxins from Dysosma versipellis (Hance).DNA-AP sites generation by etoposide in whole blood cells.Pharmacokinetically guided phase I trial of topotecan and etoposide phosphate in recurrent ovarian cancerSalvage therapy with oral etoposide in recurrent and/or metastatic squamous cell carcinoma of the head and neck.Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs.Transcriptional down-regulation and rRNA cleavage in Dictyostelium discoideum mitochondria during Legionella pneumophila infectionCytotoxic effects of human calprotectin on gastric cancer cell line is attenuated by etoposide.A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II.Dose escalation study to evaluate safety, tolerability and efficacy of intravenous etoposide phosphate administration in 27 dogs with multicentric lymphoma.Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic indexThe σ2 receptor: a novel protein for the imaging and treatment of cancer.Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme.Inositol polyphosphate multikinase is a coactivator of p53-mediated transcription and cell deathPotential of plant-derived natural products in the treatment of leukemia and lymphomaDoxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cellsIntramolecular dehydro-Diels-Alder reaction affords selective entry to arylnaphthalene or aryldihydronaphthalene lignansIntracellular uptake of etoposide-loaded solid lipid nanoparticles induces an enhancing inhibitory effect on gastric cancer through mitochondria-mediated apoptosis pathway.Nemo-like kinase is critical for p53 stabilization and function in response to DNA damage
P2860
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P2860
Etoposide: four decades of development of a topoisomerase II inhibitor
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Etoposide: four decades of development of a topoisomerase II inhibitor
@ast
Etoposide: four decades of development of a topoisomerase II inhibitor
@en
Etoposide: four decades of development of a topoisomerase II inhibitor
@nl
type
label
Etoposide: four decades of development of a topoisomerase II inhibitor
@ast
Etoposide: four decades of development of a topoisomerase II inhibitor
@en
Etoposide: four decades of development of a topoisomerase II inhibitor
@nl
prefLabel
Etoposide: four decades of development of a topoisomerase II inhibitor
@ast
Etoposide: four decades of development of a topoisomerase II inhibitor
@en
Etoposide: four decades of development of a topoisomerase II inhibitor
@nl
P3181
P1476
Etoposide: four decades of development of a topoisomerase II inhibitor
@en
P2093
P304
P3181
P356
10.1016/S0959-8049(98)00228-7
P407
P577
1998-09-01T00:00:00Z