(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases
about
Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progressDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementPlant-derived immunomodulators: an insight on their preclinical evaluation and clinical trialsProtein lysine acetylation by p300/CBPMechanism of repair of 5′-topoisomerase II–DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2Topoisomerase IIalpha maintains genomic stability through decatenation G(2) checkpoint signalingNatural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIαCleavage of plasmid DNA by eukaryotic topoisomerase II.Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosisCatalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanismRecognition and repair of chemically heterogeneous structures at DNA endsEtoposide quinone is a redox-dependent topoisomerase II poisonDietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cellsAmsacrine as a topoisomerase II poison: importance of drug-DNA interactions.The impact of green tea polyphenols on development and reproduction in Drosophila melanogaster.Oxidative metabolites of curcumin poison human type II topoisomerases.Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives.Biological clues to potent DNA-damaging activities in food and flavoring.Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.The efficacy of topoisomerase II-targeted anticancer agents reflects the persistence of drug-induced cleavage complexes in cellsEpimerization of green tea catechins during brewing does not affect the ability to poison human type II topoisomerases.DNA Topology and Topoisomerases: Teaching a "Knotty" Subject.The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothingTopoisomerase II and leukemia.Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons.Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?Natural Compounds as Anticancer Agents Targeting DNA Topoisomerases.Redox state alters anti-cancer effects of wedelolactone.Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide.Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.The Role of the MAPK Signaling, Topoisomerase and Dietary Bioactives in Controlling Cancer IncidenceMethyleugenol and oxidative metabolites induce DNA damage and interact with human topoisomerases.Anthocyanin-rich extracts suppress the DNA-damaging effects of topoisomerase poisons in human colon cancer cells.Toxicology and Safety of Flavonoids
P2860
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P2860
(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@ast
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@en
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@nl
type
label
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@ast
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@en
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@nl
prefLabel
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@ast
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@en
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@nl
P2860
P356
P1476
(-)-Epigallocatechin gallate, ...... s human type II topoisomerases
@en
P2093
Neil Osheroff
Omari J Bandele
P2860
P304
P356
10.1021/TX700434V
P407
P577
2008-04-01T00:00:00Z