Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis - Wikidata - wikimedia - TriplyDB

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

http://www.wikidata.org/entity/Q28296317

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Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?PAK1-mediated MORC2 phosphorylation promotes gastric tumorigenesis GL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling Pathways Republished: tracing PAKs from GI inflammation to cancer MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer.MDC1 Enhances Estrogen Receptor-mediated Transactivation and Contributes to Breast Cancer Suppression.By recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer.Structure, biochemistry, and biology of PAK kinases.Activated Pak4 expression correlates with poor prognosis in human gastric cancer patients.p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway.PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth.Prognostic significance of PAK4 expression in gastric cancer.Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4.MiR-199a/b-3p inhibits gastric cancer cell proliferation via down-regulating PAK4/MEK/ERK signaling pathway.

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Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

http://www.wikidata.org/entity/Q28296317

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@ast

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@en

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@nl

type

label

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@ast

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

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Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@nl

prefLabel

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@ast

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@en

Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@nl

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Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis

@en

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C Wang

http://www.w3.org/2001/XMLSchema#string

D Wang

http://www.w3.org/2001/XMLSchema#string

F Li

http://www.w3.org/2001/XMLSchema#string

F Liu

http://www.w3.org/2001/XMLSchema#string

G Wang

http://www.w3.org/2001/XMLSchema#string

H Xu

http://www.w3.org/2001/XMLSchema#string

H Zhang

http://www.w3.org/2001/XMLSchema#string

L Cao

http://www.w3.org/2001/XMLSchema#string

Y Li

http://www.w3.org/2001/XMLSchema#string

Y Zhao

http://www.w3.org/2001/XMLSchema#string

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TGF-beta signal transduction

3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins

Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element

PAK4 is activated via PI3K in HGF-stimulated epithelial cells

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1

ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-beta/Smad-induced growth arrest of prostate cells

p21-activated kinases in cancer

Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1

LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells

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scholarly article

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2379915

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10.1038/ONC.2013.300

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26

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33

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2014-06-26T00:00:00Z

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23934187

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