The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells
about
Ion channels as drug targets in central nervous system disordersTRPC channels and their implication in neurological diseasesPhysiological Function and Characterization of TRPCs in NeuronsEmerging roles of canonical TRP channels in neuronal function.Mitochondrial Ca(2+) and neurodegenerationTRPC6: an underlying target for human glaucomaTRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.TRP channels.TRPC Channels: Prominent Candidates of Underlying Mechanism in Neuropsychiatric Diseases.Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons.Emerging pathways driving early synaptic pathology in Alzheimer's disease.Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42.Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability.Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.gamma-Secretase activity modulates store-operated Ca2+ entry into rat sensory neurons.Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptakeNeurological and Motor Disorders: Neuronal Store-Operated Ca2+ Signaling: An Overview and Its Function.Age-dependent alpha-synuclein accumulation is correlated with elevation of mitochondrial TRPC3 in the brains of monkeys and mice.TRPC Channels and Parkinson's Disease.TRPC Channels and Alzheimer's Disease.On the Role of Store-Operated Calcium Entry in Acute and Chronic Neurodegenerative Diseases.
P2860
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P2860
The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
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2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
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2005年论文
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name
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@ast
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@en
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@nl
type
label
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@ast
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@en
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@nl
prefLabel
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@ast
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@en
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@nl
P2093
P1433
P1476
The overexpression of presenil ...... d Ca2+ entry into HEK293 cells
@en
P2093
Christian B Lessard
Geneviève Bourque
Guylain Boulay
Marc P Lussier
Sylvie Cayouette
P304
P356
10.1016/J.CELLSIG.2004.09.005
P407
P577
2005-04-01T00:00:00Z