Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake
about
Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migrationLysosome and calcium dysregulation in Alzheimer's disease: partners in crimeRedox regulation of store-operated Ca2+ entryAmyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.Presenilin-like GxGD membrane proteases have dual roles as proteolytic enzymes and ion channels.Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channelsMitochondrial Ca(2+) and neurodegenerationRyanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.A γ-Secretase Independent Role for Presenilin in Calcium Homeostasis Impacts Mitochondrial Function and Morphology in Caenorhabditis elegans.Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.Characterization of the ER-Targeted Low Affinity Ca(2+) Probe D4ER.Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.Mitochondrial calcium homeostasis as potential target for mitochondrial medicine.Intracellular organelles in the saga of Ca2+ homeostasis: different molecules for different purposes?Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integrationNeuronal calcium signaling: function and dysfunction.Ryanodine receptors: physiological function and deregulation in Alzheimer disease.Presenilin-2 modulation of ER-mitochondria interactions: FAD mutations, mechanisms and pathological consequences.Twenty Years of Presenilins--Important Proteins in Health and Disease.Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis.Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress.Regulators of calcium homeostasis identified by inference of kinetic model parameters from live single cells perturbed by siRNA.Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.Reply to Bezprozvanny et al.: Response to Shilling et al. (10.1074/jbc.M111.300491).Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum.Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca2+ leak in HEK293 cells.
P2860
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P2860
Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@en
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@nl
type
label
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@en
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@nl
prefLabel
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@en
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@nl
P2093
P2860
P1476
Presenilin-2 dampens intracell ...... akage and reducing Ca2+ uptake
@en
P2093
Cristina Fasolato
Cristina Florean
Enrico Zampese
Lucia Brunello
Tullio Pozzan
P2860
P304
P356
10.1111/J.1582-4934.2009.00755.X
P50
P577
2009-03-27T00:00:00Z