STAT3 as a therapeutic target in head and neck cancer - Wikidata - wikimedia - TriplyDB

STAT3 as a therapeutic target in head and neck cancer

STAT3 as a therapeutic target in head and neck cancer

http://www.wikidata.org/entity/Q28299368

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Nucleic acid-based approaches to STAT inhibition Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer Is retinol binding protein 4 a link between adiposity and cancer?SOCS, inflammation, and cancer Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression STAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinoma Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3 Dihydroartemisinin as a Putative STAT3 Inhibitor, Suppresses the Growth of Head and Neck Squamous Cell Carcinoma by Targeting Jak2/STAT3 Signaling Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines.Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.An orthotopic murine model of sinonasal malignancy.Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice.Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses.STAT3 signaling: anticancer strategies and challenges.Immune biomarkers of anti-EGFR monoclonal antibody therapy Phosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samples Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma.Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells.Receptor-tyrosine-kinase-targeted therapies for head and neck cancer.The molecular pathogenesis of head and neck cancer.JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.Signaling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis.Molecular parameters of head and neck cancer metastasis.Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancer STAT1 Activation Is Enhanced by Cisplatin and Variably Affected by EGFR Inhibition in HNSCC Cells Regulation of let-7 and its target oncogenes (Review)Lack of toxicity of a STAT3 decoy oligonucleotide.Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening.Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activity.Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.Systems biology-defined NF-kappaB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status Targeting proliferation and survival pathways in head and neck cancer for therapeutic benefit

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STAT3 as a therapeutic target in head and neck cancer

http://www.wikidata.org/entity/Q28299368

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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STAT3 as a therapeutic target in head and neck cancer

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Expert Opinion on Biological Therapy

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STAT3 as a therapeutic target in head and neck cancer

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Jennifer Rubin Grandis

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Rebecca J Leeman

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Vivian Wai Yan Lui

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P2860

Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3

A new protein containing an SH2 domain that inhibits JAK kinases

GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction

A Stat3-interacting protein (StIP1) regulates cytokine signal transduction

Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

A road map for those who don't know JAK-STAT

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

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231-41

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10.1517/14712598.6.3.231

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3

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16503733

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