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The Complex Role of STAT3 in Viral InfectionsSTAT3 inhibitors for cancer therapy: Have all roads been explored?Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cyclin D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitorsObservation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallographyThe role of IL-10 in Mycobacterium avium subsp. paratuberculosis infectionBrain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated TumorigenesisIdentifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discoveryOptimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitorsHCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell linesMolecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling.High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines.An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro.Endogenously Expressed IL-4Rα Promotes the Malignant Phenotype of Human Pancreatic Cancer In Vitro and In Vivo.Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides.Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo.Inhibiting STAT3 signaling is involved in the anti-melanoma effects of a herbal formula comprising Sophorae Flos and Lonicerae Japonicae FlosMetal complexes as potential modulators of inflammatory and autoimmune responses.Concurrent CD44s and STAT3 expression in human clear cell renal cellular carcinoma and its impact on survivalA novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells.Correlation of RKIP, STAT3 and cyclin D1 expression in pathogenesis of gastric cancer.Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors.Gastrointestinal stromal tumor - an evolving concept.Interleukin-6 induces malignant transformation of rat mesenchymal stem cells in association with enhanced signaling of signal transducer and activator of transcription 3.Concerted suppression of STAT3 and GSK3β is involved in growth inhibition of non-small cell lung cancer by Xanthatin.JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.Rap1GAP regulates renal cell carcinoma invasion.RY10-4 Inhibits the Proliferation of Human Hepatocellular Cancer HepG2 Cells by Inducing Apoptosis In Vitro and In VivoSalinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis.Tyrosine 705 Phosphorylation of STAT3 Is Associated with Phenotype Severity in TGFβ1 Transgenic Mice.Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening.Overexpression of SCLIP promotes growth and motility in glioblastoma cellsOvercoming Chemoresistance of Pediatric Ependymoma by Inhibition of STAT3 Signaling.Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.STAT3 blockade enhances the efficacy of conventional chemotherapeutic agents by eradicating head neck stemloid cancer cell.cAMP Elevation Down-Regulates β3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells.Inorganic Phosphate as a Novel Signaling Molecule with Antiproliferative Action in MDA-MB-231 Breast Cancer Cells.STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
STAT3 signaling: anticancer strategies and challenges.
@ast
STAT3 signaling: anticancer strategies and challenges.
@en
STAT3 signaling: anticancer strategies and challenges.
@nl
type
label
STAT3 signaling: anticancer strategies and challenges.
@ast
STAT3 signaling: anticancer strategies and challenges.
@en
STAT3 signaling: anticancer strategies and challenges.
@nl
prefLabel
STAT3 signaling: anticancer strategies and challenges.
@ast
STAT3 signaling: anticancer strategies and challenges.
@en
STAT3 signaling: anticancer strategies and challenges.
@nl
P2860
P356
P1476
STAT3 signaling: anticancer strategies and challenges
@en
P2860
P356
10.1124/MI.11.1.4
P577
2011-02-01T00:00:00Z