Dietary flavonoids induce MLL translocations in primary human CD34+ cells
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Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementLeukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismTopoisomerase IIalpha maintains genomic stability through decatenation G(2) checkpoint signalingDouble-strand break repair by interchromosomal recombination: an in vivo repair mechanism utilized by multiple somatic tissues in mammals.Quercetin and cancer chemopreventionToxicological aspects of the use of phenolic compounds in disease prevention.Continuous in vitro exposure to low-dose genistein induces genomic instability in breast epithelial cellsThe efficacy of topoisomerase II-targeted anticancer agents reflects the persistence of drug-induced cleavage complexes in cellsEstrogen treatment induces MLL aberrations in human lymphoblastoid cells.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.Long-term effects of chromatin remodeling and DNA damage in stem cells induced by environmental and dietary agents.Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.Risks and benefits of dietary isoflavones for cancer.Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche.Topoisomerase-mediated chromosomal break repair: an emerging player in many games.Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells.Estradiol induces gene proximity and MLL-MLLT3 fusion in an activation-induced cytidine deaminase-mediated pathway.In vitro action of flavonoids in the canine malignant histiocytic cell line DH82.Genotoxicity of dietary, environmental and therapeutic topoisomerase II poisons is uniformly correlated to prolongation of enzyme DNA residence.Cadmium is a catalytic inhibitor of DNA topoisomerase II.Prenatal exposure to flavonoids: implication for cancer risk.Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.Toxicology and Safety of FlavonoidsTranslokationen des MLL-Gens
P2860
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P2860
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@ast
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@en
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@nl
type
label
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@ast
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@en
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@nl
prefLabel
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@ast
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@en
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@nl
P2093
P356
P1433
P1476
Dietary flavonoids induce MLL translocations in primary human CD34+ cells
@en
P2093
Jan G Nijhuis
Jannie Janssen
Lou M Maas
Roger W L Godschalk
Sahar Barjesteh van Waalwijk van Doorn-Khosrovani
P304
P356
10.1093/CARCIN/BGM102
P407
P577
2007-08-01T00:00:00Z