Transport of paraquat by human organic cation transporters and multidrug and toxic compound extrusion family
about
The role of drug transporters in the kidney: lessons from tenofovirRole of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacologyA common 5'-UTR variant in MATE2-K is associated with poor response to metformin.The Concise Guide to PHARMACOLOGY 2013/14: transporters.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function.Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1Interactions of tyrosine kinase inhibitors with organic cation transporters and multidrug and toxic compound extrusion proteinsMDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells.Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity.Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.Mechanisms underlying early rapid increases in creatinine in paraquat poisoningStructure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.Deficiency of multidrug and toxin extrusion 1 enhances renal accumulation of paraquat and deteriorates kidney injury in mice.Organic cation transporters modulate the uptake and cytotoxicity of picoplatin, a third-generation platinum analogue.Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K.OCT2 and MATE1 provide bidirectional agmatine transport.Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice.Twelve transmembrane helices form the functional core of mammalian MATE1 (multidrug and toxin extruder 1) proteinThe Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy VolunteersStructure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3Characterization of the disposition and toxicokinetics of N-butylpyridinium chloride in male F-344 rats and female B6C3F1 mice and its transport by organic cation transporter 2Substrate-dependent inhibition of human MATE1 by cationic ionic liquids.Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomicsMammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics.Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans.Clathrin-Dependent Uptake of Paraquat into SH-SY5Y Cells and Its Internalization into Different Subcellular Compartments.Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine.Cycloartenyl Ferulate Inhibits Paraquat-Induced Apoptosis in HK-2 Cells With the Involvement of ABCC1.Xenobiotic transporters and kidney injury.The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization.Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule.Beyond drug-drug interactions: effects of transporter inhibition on endobiotics, nutrients and toxins.Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO).
P2860
Q26866489-0C948C9E-2B31-49EF-9336-8881C1BA267BQ27026858-BEB0F978-02AA-4AE9-8C4B-AE4A66C66C46Q30407583-6A5329FC-FE77-4389-89B8-4BAD0D9EB6F6Q30486743-0F826198-BFC4-4021-A067-4E3B54BEADB6Q33714593-9AAB08B6-F445-49E6-9361-FB7A04688A1EQ33907033-59BF6E06-B886-4AC8-8994-205873C2EE16Q34170589-7D608BC0-1064-42D4-8D19-C9386773E103Q34292530-D5C859E1-5C67-4291-8330-7EBCD685F7FCQ34714353-B184F457-FE10-4BE3-8BE8-E991E8D708EAQ34736271-E7AD5B54-5078-479C-9570-1157C45D175BQ34974839-3492D09D-A61B-4D7E-8A50-5D3B4EF6A865Q35014972-FAC0F509-601E-4875-B735-DE70DAAC2BD8Q35224245-13413227-CDBC-499D-935D-EE3AB19F0980Q35229337-59449D0A-C6F8-403C-B859-8082D70DCFE1Q35591362-1C2CE970-82D1-4CAA-ADA8-98155D172233Q35671906-4EB7654A-A559-4ECD-B94F-D88780367B06Q35996683-DDFBE2B2-74C9-477D-8ECD-6BC90E4DAD09Q36110018-F45726BE-7B22-4806-8F4D-5A939F722B26Q36176040-FD9CBA0D-2520-4AA7-8CDB-D5FBA598C116Q36201747-EA2BAC21-8561-488C-9C48-1F8046B25884Q36689589-7DADED2F-4975-4DF6-AA8F-24EDEBB0BC5AQ36747640-9A3DB8E7-D65B-40F9-AC47-A503FEFDC0ECQ36784291-6983B8E4-8474-4B7F-8365-70401F6A45DFQ37188035-113C4934-496C-404E-B267-95BDAA389AB2Q37422651-C9E3A24B-A008-4BB2-ACA7-C957472ABFCAQ37860362-7499D2DF-58E9-41F2-9738-DFF00397E405Q37933394-F4620ED1-7C1F-48C8-9029-F0363297068FQ37969214-BD51EE2C-F494-404C-9ECB-EA0EC0FAFDA0Q38700355-8FF1183D-93CA-40B6-8F59-90C9A3C14486Q38711894-0AC94B3D-D23D-4ACF-9D41-929A75B67083Q38831370-03ED679D-9B44-49DA-AFF7-4B60604F0558Q38836232-86DBF529-C24D-4F13-B2AB-6F6C75FD0E74Q39098252-A81E59AE-C9E1-4402-833C-77E57F63E1DAQ41655897-819787AA-F41E-4B34-8247-B422B5857DAFQ42644926-DC3F3528-CC8C-42A5-842F-48B698182BC3Q46055973-370AD04B-630C-4522-9E95-6773261CCB01Q47895958-68F6BA08-E021-4304-BCA9-E061C35282C0Q55259139-CAFA0D3E-4A91-4513-92B9-81E434131062
P2860
Transport of paraquat by human organic cation transporters and multidrug and toxic compound extrusion family
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Transport of paraquat by human ...... oxic compound extrusion family
@ast
Transport of paraquat by human ...... oxic compound extrusion family
@en
Transport of paraquat by human ...... oxic compound extrusion family
@nl
type
label
Transport of paraquat by human ...... oxic compound extrusion family
@ast
Transport of paraquat by human ...... oxic compound extrusion family
@en
Transport of paraquat by human ...... oxic compound extrusion family
@nl
prefLabel
Transport of paraquat by human ...... oxic compound extrusion family
@ast
Transport of paraquat by human ...... oxic compound extrusion family
@en
Transport of paraquat by human ...... oxic compound extrusion family
@nl
P2093
P3181
P356
P1476
Transport of paraquat by human ...... oxic compound extrusion family
@en
P2093
Kathleen M Giacomini
Marco Sorani
Shuzhong Zhang
P304
P3181
P356
10.1124/JPET.107.123554
P407
P577
2007-08-01T00:00:00Z