Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins
about
A short guided tour through functional and structural features of saposin-like proteinsGranulysin-mediated tumor rejection in transgenic miceBiology and clinical relevance of granulysinFusion of green fluorescent protein to the C-terminus of granulysin alters its intracellular localization in comparison to the native moleculeGranule-dependent cytolysis of Mycobacterium tuberculosis-infected macrophages by human gammadelta+ T cells has no effect on intracellular mycobacterial viabilityCytotoxic proteins and therapeutic targets in severe cutaneous adverse reactionsAntimicrobial Properties of an Immunomodulator - 15 kDa Human GranulysinExpression, processing and transcriptional regulation of granulysin in short-term activated human lymphocytes.Enrichment and analysis of secretory lysosomes from lymphocyte populationsMapping and genotypic analysis of the NK-lysin gene in chicken.Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function.Expression and purification of 15 kDa granulysin utilizing an insect cell secretion system.Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.Regulation and gene expression profiling of NKG2D positive human cytomegalovirus-primed CD4+ T-cells.Induction of granulysin and perforin cytolytic mediator expression in 10-week-old infants vaccinated with BCG at birth.Cell death mechanisms at the maternal-fetal interface: insights into the role of granulysin.15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.In vivo potential of recombinant granulysin against human tumors.Expression of the Bovine NK-Lysin Gene Family and Activity against Respiratory Pathogens.Association of GNLY genetic polymorphisms with chronic liver disease in a Korean population.Self-recognition of CD1 by gamma/delta T cells: implications for innate immunityCharacterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.Bovine NK-lysin: Copy number variation and functional diversification.Granule exocytosis of granulysin and granzyme B as a potential key mechanism in vaccine-induced immunity in cattle against the nematode Ostertagia ostertagi.An atomic-force basis for the bacteriolytic effects of granulysin.Granulysin produced by uterine natural killer cells induces apoptosis of extravillous trophoblasts in spontaneous abortionSingle-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafishPotential function of granulysin, other related effector molecules and lymphocyte subsets in patients with TB and HIV/TB coinfection.Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humansNovel therapeutic vaccines [(HSP65 + IL-12)DNA-, granulysin- and Ksp37-vaccine] against tuberculosis and synergistic effects in the combination with chemotherapy.The immunological functions of saposins.Structural and Functional Consequences Induced by Post-Translational Modifications in α-Defensins.Acholeplasma laidlawii up-regulates granulysin gene expression via transcription factor activator protein-1 in a human monocytic cell line, THP-1.Opposing roles of activator protein-1 and CCAAT/enhancer binding protein beta in the regulation of inducible granulysin gene expression in a human monocytic cell line, THP-1.Necrosis versus apoptosis as the mechanism of target cell death induced by Entamoeba histolytica.NK-lysin and its shortened analog NK-2 exhibit potent activities against Trypanosoma cruziInteraction of NK lysin, a peptide produced by cytolytic lymphocytes, with endotoxin.Entamoeba histolytica induces host cell death in amebic liver abscess by a non-Fas-dependent, non-tumor necrosis factor alpha-dependent pathway of apoptosisGranulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes.Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES.
P2860
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P2860
Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Processing, subcellular locali ...... small, lytic, granule proteins
@ast
Processing, subcellular locali ...... small, lytic, granule proteins
@en
Processing, subcellular locali ...... small, lytic, granule proteins
@nl
type
label
Processing, subcellular locali ...... small, lytic, granule proteins
@ast
Processing, subcellular locali ...... small, lytic, granule proteins
@en
Processing, subcellular locali ...... small, lytic, granule proteins
@nl
prefLabel
Processing, subcellular locali ...... small, lytic, granule proteins
@ast
Processing, subcellular locali ...... small, lytic, granule proteins
@en
Processing, subcellular locali ...... small, lytic, granule proteins
@nl
P2093
P3181
P1476
Processing, subcellular locali ...... small, lytic, granule proteins
@en
P2093
A M Krensky
D A Hanson
T J Goralski
P304
P3181
P407
P577
1997-03-15T00:00:00Z