Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin. - Wikidata - wikimedia - TriplyDB

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

http://www.wikidata.org/entity/Q34310509

about

Idiosyncratic adverse drug reactions: current concepts Postulates for validating TLR4 agonists Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes Cytotoxic proteins and therapeutic targets in severe cutaneous adverse reactions Lamotrigine-induced toxic epidermal necrolysis confirmed by in vitro granulysin and cytokine assays.15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level.Prothymosin α and a prothymosin α-derived peptide enhance T(H)1-type immune responses against defined HER-2/neu epitopes.Evaluation of two mutants of Mycobacterium avium subsp. paratuberculosis as candidates for a live attenuated vaccine for Johne's disease.The peripheral blood transcriptome reflects variations in immunity traits in swine: towards the identification of biomarkers.Innate and adaptive immune responses to cell death.Cell death mechanisms at the maternal-fetal interface: insights into the role of granulysin.β-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-α production by human plasmacytoid dendritic cells, and promote inflammation.High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.Crohn's disease and Mycobacterium avium subsp. paratuberculosis: the need for a study is long overdue.15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.In vivo potential of recombinant granulysin against human tumors.Human NK cell lytic granules and regulation of their exocytosis Granule exocytosis of granulysin and granzyme B as a potential key mechanism in vaccine-induced immunity in cattle against the nematode Ostertagia ostertagi.Evaluation of the Immunomodulatory Activity of the Chicken NK-Lysin-Derived Peptide cNK-2.Trauma alarmins as activators of damage-induced inflammation.Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis: a comparative review.Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN): could retinoids play a causative role?Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: An Update.Cytotoxic potential of decidual NK cells and CD8+ T cells awakened by infections.Natural killer and dendritic cells collaborate in the immune response induced by the vaccine against uterine cervical cancer.Applying the One Health Concept to Mycobacterial Research - Overcoming Parochialism.Analysis of granulysin-mediated cytotoxicity in peripheral blood of patients with psoriatic arthritis.Inhalation of recombinant adenovirus expressing granulysin protects mice infected with Mycobacterium tuberculosis.Granulysin expression increases with increasing clinical severity of psoriasis.Recent progress of elucidating the mechanisms of drug hypersensitivity.Association of natural killer cell dysfunction and recurrent Stevens-Johnson syndrome in a pediatric patient.Granulysin expressed in a humanized mouse model induces apoptotic cell death and suppresses tumorigenicity.Alarmins and immunity.Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions.Alarmin-induced cell migration.Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy.Pretreatment serum level of 15-kDa granulysin might have a prognostic value in patients with diffuse large B cell lymphoma.Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion The Role of Granulysin in Cancer Immunology

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P2860

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

http://www.wikidata.org/entity/Q34310509

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@ast

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@en

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@nl

type

label

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@ast

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@en

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@nl

prefLabel

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@ast

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@en

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@nl

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BLOOD-2010-03-273953

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Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

@en

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Alan M Krensky

http://www.w3.org/2001/XMLSchema#string

Carol Clayberger

http://www.w3.org/2001/XMLSchema#string

De Yang

http://www.w3.org/2001/XMLSchema#string

Gonzalo de la Rosa

http://www.w3.org/2001/XMLSchema#string

Joost J Oppenheim

http://www.w3.org/2001/XMLSchema#string

Michael W Finn

http://www.w3.org/2001/XMLSchema#string

Poonam Tewary

http://www.w3.org/2001/XMLSchema#string

Yana Li

http://www.w3.org/2001/XMLSchema#string

P2860

Granulysin-mediated tumor rejection in transgenic mice

Granulysin crystal structure and a structure-derived lytic mechanism

Biosynthesis of granulysin, a novel cytolytic molecule

Granulysin in human serum as a marker of cell-mediated immunity

A distinct pathway of cell-mediated apoptosis initiated by granulysin

CD8 T cell-mediated killing of Cryptococcus neoformans requires granulysin and is dependent on CD4 T cells and IL-15

Granulysin, a cytolytic molecule, is also a chemoattractant and proinflammatory activator

Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection

Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

P304

3465-3474

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scholarly article

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10.1182/BLOOD-2010-03-273953

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P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

116

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P577

2010-07-21T00:00:00Z

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P5875

45365894

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P698

20660289

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P921

Toll-like receptor

P932

2981473

http://www.w3.org/2001/XMLSchema#string