PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
about
PIAS1 interacts with FLASH and enhances its co-activation of c-MybInteraction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1PARP-1 transcriptional activity is regulated by sumoylation upon heat shockSumoylation of the zinc finger protein ZXDC enhances the function of its transcriptional activation domainPIAS3 promotes homology‑directed repair and distal non‑homologous end joiningThe impact of the Cancer Genome Atlas on lung cancer.Signal transducer and activator of transcription 5A/B in prostate and breast cancersEbola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machineryTnaA, an SP-RING protein, interacts with Osa, a subunit of the chromatin remodeling complex BRAHMA and with the SUMOylation pathway in Drosophila melanogasterPIAS3 expression in squamous cell lung cancer is low and predicts overall survival.Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function.Identification of JAK/STAT pathway regulators--insights from RNAi screensNarrative-based computational modelling of the Gp130/JAK/STAT signalling pathway.A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcriptionPhosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1.SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation.Novel role and mechanism of protein inhibitor of activated STAT1 in spatial learning.PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms.SUMOylation by the E3 ligase TbSIZ1/PIAS1 positively regulates VSG expression in Trypanosoma brucei.Canonical and non-canonical JAK-STAT signaling.PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cellsPIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleusTranscriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).Functional characterization of DnSIZ1, a SIZ/PIAS-type SUMO E3 ligase from Dendrobium.Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation.Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathwaysA role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors.Emerging roles of the SUMO pathway in mitosisp53 sumoylation: mechanistic insights from reconstitution studies.Arabidopsis HIGH PLOIDY2 Sumoylates and Stabilizes Flowering Locus C through Its E3 Ligase ActivitySumo-1 function is dispensable in normal mouse development.PIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer.Decreased recognition of SUMO-sensitive target genes following modification of SF-1 (NR5A1).Protein interactions in the sumoylation cascade: lessons from X-ray structures.Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomasCooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer.The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependent.The 'ubiquitous' reality of vector immunology.SUMO rules: regulatory concepts and their implication in neurologic functions.SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin.
P2860
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P2860
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@ast
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@en
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@nl
type
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PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@ast
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@en
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@nl
prefLabel
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@ast
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@en
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@nl
P3181
P356
P1433
P1476
PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases?
@en
P2093
Andrew D Sharrocks
P3181
P356
10.1101/GAD.1421006
P407
P577
2006-04-01T00:00:00Z