Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas
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Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expressionGlioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotypeConsensus on the role of human cytomegalovirus in glioblastomaAberrant expression of interleukin-1β and inflammasome activation in human malignant gliomasNF-κB and STAT3 in glioblastoma: therapeutic targets coming of ageSTAT3: A Novel Molecular Mediator of Resistance to ChemoradiotherapyMolecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug developmentMetabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficaciesAPE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalLoss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesisEvidence from a large-scale meta-analysis indicates eczema reduces the incidence of gliomaLoss of SH3GL2 promotes the migration and invasion behaviours of glioblastoma cells through activating the STAT3/MMP2 signalling.STAT6 expression in glioblastoma promotes invasive growthA novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion.Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro.Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapyStat3-positive tumor cells contribute to vessels neoformation in primary central nervous system lymphomaSorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3Involvement of the janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis.Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations.Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model.Transcriptional regulation of adrenomedullin by oncostatin M in human astroglioma cells: implications for tumor invasion and migrationAssociation of pSTAT3-VEGF signaling pathway with peritumoral edema in newly diagnosed glioblastoma: an immunohistochemical study.STAT3 silencing inhibits glioma single cell infiltration and tumor growthThe expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patientsAdenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251.Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling.ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer.Therapeutic potential of AZD1480 for the treatment of human glioblastomaCritical functions of RhoB in support of glioblastoma tumorigenesisRecent developments on immunotherapy for brain cancer.Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional ActivitySOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor CellsInterleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A EpendymomaDARPP32, STAT5 and STAT3 mRNA expression ratios in glioblastomas are associated with patient outcome.PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling.High expression of WDR1 in primary glioblastoma is associated with poor prognosis.Biologically targeted therapeutics in pediatric brain tumors.
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Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Signal transducer and activato ...... signaling pathways in gliomas
@en
Signal transducer and activato ...... signaling pathways in gliomas.
@nl
type
label
Signal transducer and activato ...... signaling pathways in gliomas
@en
Signal transducer and activato ...... signaling pathways in gliomas.
@nl
prefLabel
Signal transducer and activato ...... signaling pathways in gliomas
@en
Signal transducer and activato ...... signaling pathways in gliomas.
@nl
P2860
P1476
Signal transducer and activato ...... signaling pathways in gliomas
@en
P2093
Emily C Brantley
Etty N Benveniste
P2860
P304
P356
10.1158/1541-7786.MCR-07-2180
P577
2008-05-01T00:00:00Z