Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
about
Down syndrome and leukemia: insights into leukemogenesis and translational targetsThe biology of pediatric acute megakaryoblastic leukemiaMyeloid leukemia in Down syndromeThe emerging role of GATA transcription factors in development and diseaseETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cellsTreatment and prognostic impact of transient leukemia in neonates with Down syndromeSerum thrombopoietin level and thrombocytopenia during the neonatal period in infants with Down's syndrome.Distinctive hematological abnormalities in East Asian neonates and children with Down syndrome.The prenatal origins of cancerDevelopmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesisTransient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder.Genome-wide expression analysis in Down syndrome: insight into immunodeficiency.Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathologyNatural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971.Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.Myeloid Proliferations Associated with Down Syndrome.Trisomy 21 enhances human fetal erythro-megakaryocytic development.Perturbation of fetal hematopoiesis in a mouse model of Down syndrome's transient myeloproliferative disorderInsights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndromeDevelopment of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes.Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.Unique clinical and biological features of leukemia in Down syndrome children.Haematopoietic development and leukaemia in Down syndrome.Evolution of myeloid leukemia in children with Down syndrome.Distinct GATA1 Point Mutations in Monozygotic Twins With Down Syndrome and Transient Abnormal Myelopoiesis From a Triplet Pregnancy: A Case Report and Review of Literature.Predispositions to Leukemia in Down Syndrome and Other Hereditary Disorders.French retrospective multicentric study of neonatal hemochromatosis: importance of autopsy and autoimmune maternal manifestations.Blast cell deficiency of CD11a as a marker of acute megakaryoblastic leukemia and transient myeloproliferative disease in children with and without Down syndrome.Acute myeloid leukaemia at an early age: Reviewing the interaction between pesticide exposure and KMT2A-rearrangement.Detection of mutations in GATA1 gene using automated denaturing high-performance liquid chromatography and direct sequencing in children with Down syndrome.Extensive placental choriovascular infiltration by maturing myeloid cells in down syndrome-associated transient abnormal myelopoiesis.Exchange transfusion in patients with Down syndrome and severe transient leukemia.Successful Liver Transplantation for Transient Abnormal Myelopoiesis-Associated Liver Failure.Liver disease is frequently observed in Down syndrome patients with transient abnormal myelopoiesis.Transient myeloproliferative disorder and GATA1 mutation in neonates with and without Down syndrome.Transient abnormal myelopoiesis in a phenotypically normal newborn with polyclonal trisomy 21
P2860
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P2860
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@ast
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@en
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@nl
type
label
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@ast
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@en
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@nl
prefLabel
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@ast
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@en
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@nl
P2093
P1433
P1476
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
@en
P2093
Changhong Yin
Charlotte M Druschel
Claudio Sandoval
Qianxu Guo
Sharon R Pine
Somasundaram Jayabose
P304
P356
10.1182/BLOOD-2007-01-069542
P407
P577
2007-09-15T00:00:00Z