Structural relationship of epipolythiodioxopiperazines and their immunomodulating activity
about
Rational and combinatorial tailoring of bioactive cyclic dipeptidesEpidithiodioxopiperazines. occurrence, synthesis and biogenesisPhytotoxic secondary metabolites and peptides produced by plant pathogenic Dothideomycete fungiThe mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in miceThe Epipolythiodiketopiperazine Gene Cluster in Claviceps purpurea: Dysfunctional Cytochrome P450 Enzyme Prevents Formation of the Previously Unknown ClapurinesRedox sensitive epidithiodioxopiperazines in biological mechanisms of toxicity.Synthesis and Anticancer Activity of Epipolythiodiketopiperazine AlkaloidsSea foam as a source of fungal inoculum for the isolation of biologically active natural products.Synthetic Studies Towards MPC1001: Preparation of a β-hydroxyl-Tyrosine Derivative.In vivo immunosuppressive activity of gliotoxin, a metabolite produced by human pathogenic fungi.The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis.Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC.The biocontaminants and complexity of damp indoor spaces: more than what meets the eyes.The past, present and future of secondary metabolite research in the Dothideomycetes.Gliotoxin--bane or boon?Plasma pharmacokinetics and bioavailability of verticillin A following different routes of administration in mice using liquid chromatography tandem mass spectrometry.A new gliotoxin analogue from a marine-derived fungus Aspergillus fumigatus Fres.Clinical validity of bis(methylthio)gliotoxin for the diagnosis of invasive aspergillosis.A novel redox mechanism for the glutathione-dependent reversible uptake of a fungal toxin in cells.Nuclear factor-kappa B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin.Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK.Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.Immunomodulation of human fetal cells by the fungal metabolite gliotoxin.Exacerbation of invasive aspergillosis by the immunosuppressive fungal metabolite, gliotoxin.
P2860
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P2860
Structural relationship of epipolythiodioxopiperazines and their immunomodulating activity
description
1986 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1986
@ast
im Februar 1986 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: February 1986)
@en
vedecký článok (publikovaný 1986-02)
@sk
vědecký článek publikovaný v roce 1986
@cs
wetenschappelijk artikel (gepubliceerd in 1986-02)
@nl
наукова стаття, опублікована в лютому 1986
@uk
научни чланак (објављен 1986-02)
@sr
name
Structural relationship of epi ...... heir immunomodulating activity
@ast
Structural relationship of epi ...... heir immunomodulating activity
@en
Structural relationship of epi ...... heir immunomodulating activity
@nl
type
label
Structural relationship of epi ...... heir immunomodulating activity
@ast
Structural relationship of epi ...... heir immunomodulating activity
@en
Structural relationship of epi ...... heir immunomodulating activity
@nl
prefLabel
Structural relationship of epi ...... heir immunomodulating activity
@ast
Structural relationship of epi ...... heir immunomodulating activity
@en
Structural relationship of epi ...... heir immunomodulating activity
@nl
P2093
P3181
P1433
P1476
Structural relationship of epi ...... heir immunomodulating activity
@en
P2093
A Müllbacher
R D Eichner
U Tiwari-Palni
P3181
P356
10.1016/0161-5890(86)90047-7
P407
P577
1986-02-01T00:00:00Z