The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.
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Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeACytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the BionectriaceaePathogenesis of Aspergillus fumigatus in Invasive AspergillosisGliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulenceAspergillus fumigatus: principles of pathogenesis and host defenseNuclear factor-kappaB activity is down-regulated in nasal polyps from aspirin-sensitive asthmaticsPhytotoxic secondary metabolites and peptides produced by plant pathogenic Dothideomycete fungiQuantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in miceThe ubiquitin-proteasome pathway and proteasome inhibitorsThe mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in miceAspergillus fumigatus and aspergillosisCurrent status of novel antifibrotic therapies in patients with chronic liver diseasePseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells.Selective inactivation of glutaredoxin by sporidesmin and other epidithiopiperazinedionesDetection of gliotoxin in experimental and human aspergillosisHealthy human T-Cell Responses to Aspergillus fumigatus antigens.Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway.Vascular injury involves the overoxidation of peroxiredoxin type II and is recovered by the peroxiredoxin activity mimetic that induces reendothelialization.Putative virulence factors of Aspergillus fumigatus.Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites.Redox sensitive epidithiodioxopiperazines in biological mechanisms of toxicity.Natural products as targeted modulators of the nuclear factor-kappaB pathway.The mycotoxins citrinin, gliotoxin, and patulin affect interferon-gamma rather than interleukin-4 production in human blood cells.Inhibiting NF-κB activation by small molecules as a therapeutic strategy.An antimicrobial diketopiperazine alkaloid and co-metabolites from an endophytic strain of Gliocladium isolated from Strychnos cf. toxifera.Synthesis and Anticancer Activity of Epipolythiodiketopiperazine AlkaloidsAntifungal and antihepatotoxic effects of sepia ink extract against oxidative stress as a risk factor of invasive pulmonary aspergillosis in neutropenic miceRsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis.What do we know about the role of gliotoxin in the pathobiology of Aspergillus fumigatus?Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humansGβ-like CpcB plays a crucial role for growth and development of Aspergillus nidulans and Aspergillus fumigatusTumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1.A novel C2H2 transcription factor that regulates gliA expression interdependently with GliZ in Aspergillus fumigatus.Flice inhibitory protein is associated with the survival of neonatal neutrophilsNuclear factor-kappa B inhibitors as potential novel anti-inflammatory agents for the treatment of immune glomerulonephritisThe ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.Export of hepatitis B virus RNA on a Rev-like pathway: inhibition by the regenerating liver inhibitory factor IkappaB alpha.Polarized response of endothelial cells to invasion by Aspergillus fumigatus.Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone.The immune response to fungal infections.
P2860
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P2860
The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@ast
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@en
type
label
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@ast
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@en
prefLabel
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@ast
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@en
P2093
P2860
P356
P1476
The immunosuppressive fungal m ...... ranscription factor NF-kappaB.
@en
P2093
A Mühlbacher
A P Czernilofsky
E B Traenckner
K Schulze-Osthoff
P A Baeuerle
P2860
P304
P356
10.1084/JEM.183.4.1829
P407
P577
1996-04-01T00:00:00Z