Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins
about
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormonesThe crystal structure of rat liver AKR7A1. A dimeric member of the aldo-keto reductase superfamilyA cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13Temporal and spatial patterns of ovarian gene transcription following an ovulatory dose of gonadotropin in the ratThe pattern of amino acid replacements in alpha/beta-barrels.Stereoisomeric specificity of the retinoid cycle in the vertebrate retina.Highly diverse protein library based on the ubiquitous (β/α)₈ enzyme fold yields well-structured proteins through in vitro folding selection.Aldo-keto reductases and formation of polycyclic aromatic hydrocarbon o-quinones.Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytesExtreme makeover: Engineering the activity of a thermostable alcohol dehydrogenase (AdhD) from Pyrococcus furiosus.Acceleration of an aldo-keto reductase by minimal loop engineeringComparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen.Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis.Engineering the substrate specificity of Staphylococcus aureus Sortase A. The beta6/beta7 loop from SrtB confers NPQTN recognition to SrtA.Modular exchange of substrate-binding loops alters both substrate and cofactor specificity in a member of the aldo-keto reductase superfamily
P2860
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P2860
Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Conversion of mammalian 3alpha ...... y from androgens to progestins
@ast
Conversion of mammalian 3alpha ...... y from androgens to progestins
@en
Conversion of mammalian 3alpha ...... y from androgens to progestins
@nl
type
label
Conversion of mammalian 3alpha ...... y from androgens to progestins
@ast
Conversion of mammalian 3alpha ...... y from androgens to progestins
@en
Conversion of mammalian 3alpha ...... y from androgens to progestins
@nl
prefLabel
Conversion of mammalian 3alpha ...... y from androgens to progestins
@ast
Conversion of mammalian 3alpha ...... y from androgens to progestins
@en
Conversion of mammalian 3alpha ...... y from androgens to progestins
@nl
P2860
P356
P1476
Conversion of mammalian 3alpha ...... y from androgens to progestins
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.20.11161
P407
P577
1999-09-28T00:00:00Z