Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.
about
A short guided tour through functional and structural features of saposin-like proteinsThe Gup1 homologue of Trypanosoma brucei is a GPI glycosylphosphatidylinositol remodelase.Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness.Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited.Chapter 2: Kill the bacteria...and also their messengers?KREX2 is not essential for either procyclic or bloodstream form Trypanosoma brucei.The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei.A Gene of the β3-Glycosyltransferase Family Encodes N-Acetylglucosaminyltransferase II Function in Trypanosoma bruceiTrypanosome glycosylphosphatidylinositol biosynthesis.Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei.Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite.Tolerance of glycosylphosphatidylinositol (GPI)-specific phospholipase D overexpression by Chinese hamster ovary cell mutants with aberrant GPI biosynthesis.Removal or maintenance of inositol-linked acyl chain in glycosylphosphatidylinositol is critical in trypanosome life cycle.Crystal structure of the mammalian lipopolysaccharide detoxifier.The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei
P2860
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P2860
Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.
description
2001 nî lūn-bûn
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2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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name
Purification, cloning and char ...... cylase from Trypanosoma brucei
@nl
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@ast
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@en
type
label
Purification, cloning and char ...... cylase from Trypanosoma brucei
@nl
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@ast
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@en
prefLabel
Purification, cloning and char ...... cylase from Trypanosoma brucei
@nl
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@ast
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@en
P2093
P2860
P921
P3181
P356
P1433
P1476
Purification, cloning and char ...... ylase from Trypanosoma brucei.
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/20.17.4923
P407
P577
2001-09-01T00:00:00Z