Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells - Wikidata - wikimedia - TriplyDB

Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

http://www.wikidata.org/entity/Q28364060

about

Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes.Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress Control of cell growth by the SCF and APC/C ubiquitin ligases The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.Acm1 is a negative regulator of the CDH1-dependent anaphase-promoting complex/cyclosome in budding yeast.The DNA damage response mediator MDC1 directly interacts with the anaphase-promoting complex/cyclosome The tumor suppressor WARTS activates the Omi / HtrA2-dependent pathway of cell death WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase Dual mode of degradation of Cdc25 A phosphatase Ubiquitin and SUMO systems in the regulation of mitotic checkpoints Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency Meiosis I is established through division-specific translational control of a cyclin The APC/C inhibitor, Emi1, is essential for prevention of rereplication LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression Oscillation of APC/C activity during cell cycle arrest promotes centrosome amplification.The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress.Clathrin is spindle-associated but not essential for mitosis.The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair.Regulation and roles of Cdc7 kinase under replication stress.The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.The chicken as a model for large-scale analysis of vertebrate gene function.APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.Control of the centriole and centrosome cycles by ubiquitination enzymes.The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1.Endoreduplication and activation of the anaphase-promoting complex during symbiotic cell development.Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit.Comparison of gene expression response to neutron and x-ray irradiation using mouse blood Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells.Phosphorylation-triggered CUEDC2 degradation promotes UV-induced G1 arrest through APC/C(Cdh1) regulation.Securin is a target of the UV response pathway in mammalian cells DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest.Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression.Molecular-targeted therapies for ovarian cancer: prospects for the future.

P2860

Q21195153-96BE0C7D-CB19-45BF-808B-D248393B0CFC Q24298032-A40CD20F-292C-40D0-B46E-4362C63862E6 Q24317772-BF17F40D-C8C6-47EF-9C2A-AF6433AF23C2 Q24534348-A1919112-1F18-4268-ADA6-FD575CE30618 Q24559993-B3D9455D-A635-4E3E-A900-A4CB61ECB9AB Q24647543-ADE79624-ED55-4331-8E25-00DC0921233C Q26777305-E7030681-25B6-4A54-891F-5D5473029CEF Q27331358-BD8B3124-1FA6-4B05-804F-4A1C0EA7B6A1 Q27933747-A3F36066-0FFA-4E54-BB33-50F467A50960 Q28247374-481C7EE3-023F-4482-80BE-3F4AEA10A8BC Q28260835-2B27B35A-81D3-452D-923F-ACB72EFC9396 Q28283832-E18DB3C2-2E2B-4773-98F2-9191493882E1 Q28386155-FAE86A35-C616-47BD-B612-4C690C2415B0 Q28387076-0F55B934-018D-46C6-89C8-D6414D2C07AB Q28511152-9C95B6A0-5B70-47A0-8F43-C0D687FD15B3 Q29346871-DC73A3D3-5959-4A0B-8188-E9D1FCBD99DE Q30442630-12AD35C9-17DF-4181-8CEC-1304722F004A Q30522305-A6E0BFE9-D7ED-4DD3-806C-8E2C7E997070 Q30573133-1C537978-AED5-4FEF-BACD-30B14E9B3432 Q31059949-EEDDD264-CC24-4ADB-8C62-72CA185BF8B7 Q33366492-F48FBA84-486D-466B-B464-AB10197F23A6 Q33804824-2F468645-6B77-44A4-AE0E-26E27BFE966C Q33861736-C61ED368-22DA-44E1-A93F-A5981CCE472F Q33953075-83C5D18A-305E-4312-BBB1-E97D2A7FDD7F Q34045733-8882E86C-F0FC-4601-9330-A13B8FA05078 Q34174218-C5495ED6-9C0C-4BEA-A3FA-536BE8DF8AC0 Q34806918-56F5A176-EB22-45F5-82D0-A1FA82D8F787 Q34818293-BEE3C094-896B-4ED4-AC0D-38CC8C1F44E3 Q35004565-E6AB1211-C83D-4FAB-8285-B476DB35BF5F Q35488924-DE18DC6F-037C-4BC6-8909-0635AD01D1A8 Q35785925-743AE2D8-7F38-4166-AB8A-620FB0DB30BB Q35787361-CC41FF9B-F403-42AF-B173-5E1D1A610EDE Q36238838-25E2B4B8-113C-4522-B411-9E8DE5C8D0D9 Q36322375-4E83EE6E-C2A6-44D0-8950-CC5486A97337 Q36990776-52412E49-293A-4227-AAAF-5E6A45F8E81C Q37012717-2A9D909E-42BA-41CA-B89C-1692563684E5 Q37146681-776CAF64-A9B3-435A-929B-CA19FA6C55A6 Q37262174-96810FB1-B88A-4721-BCEC-1B86A65D6C9B Q37614211-8264E130-6AEC-4981-B26D-E89975D74546 Q38036942-EE873E36-2FC5-4EE7-AB9D-F313D666BBCC

P2860

Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

http://www.wikidata.org/entity/Q28364060

description

2001 nî lūn-bûn

@nan

2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@ast

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@en

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@nl

type

label

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@ast

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@en

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@nl

prefLabel

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@ast

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@en

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@nl

P1433

Q28364060-7176563A-7870-44DC-9A67-993F2B10E854

P1476

Q28364060-9A00DF46-E915-4BEF-8F1D-316F88ED6710

P2093

Q28364060-2D470487-4C8D-418C-9006-CEE51257813A

Q28364060-3D554690-5BD1-441C-B4DE-A162C4822CA5

Q28364060-4525C0EE-9079-424D-94F3-F55F61C6A761

Q28364060-6E917FFA-B0E2-4B9B-BC11-7968F90CBC35

Q28364060-A53C4C5D-535F-4EAA-98B1-6E6358DB094F

Q28364060-E3AEE405-50D9-4D93-8D13-A8BA5A5A48C2

P2860

Q28364060-0ADC9897-96A4-4A50-B229-0C74B1817934

Q28364060-12AD55E4-0928-4985-837D-45A2A303914A

Q28364060-1DE5340C-60B9-46BE-B172-1B775D5065A5

Q28364060-2275F9DC-B01F-4E39-B6BC-135EE7326DCF

Q28364060-2900D093-ADAB-4ACD-AA36-0242E0A2AC6E

Q28364060-3753C566-107D-4ADE-B181-C27D8827EAD3

Q28364060-3A104E52-D3B0-48C4-995D-06C29801C71E

Q28364060-4279FA80-797A-4B45-BB77-A06515FEE9EF

Q28364060-44C21313-35AD-424C-946E-4B80164F0DD6

Q28364060-45310D23-8DBC-411F-A1DB-1C5D024DDF8A

P304

Q28364060-D30E4203-828C-4D75-996A-41E97FB65FF3

P31

Q28364060-E65ABC67-AAA6-4630-9624-9CE7D94F14AC

P3181

Q28364060-03FE7BBB-E7AB-4189-A890-00A506CB9771

P356

Q28364060-653E0AB2-6D55-4EC7-BCC1-F59B836756C7

P407

Q28364060-16C37C47-FF91-4E99-AAA5-5F546061DA84

P433

Q28364060-3FEFCFC3-EAF4-4794-B7A5-402620ABAEBE

P478

Q28364060-49847AD7-F6CB-4A0C-A1C1-18F0BF509E7C

P50

Q28364060-90D9DD92-7922-4373-93B4-CC4E8B701906

P577

Q28364060-CE68BEF2-DECC-417C-8F40-8AEEB2C8A751

P5875

Q28364060-1DA3D55C-A7B8-4950-A0A7-C17B59949B63

P698

Q28364060-CB2A6246-759F-4F8F-ABD8-036B2C9DB901

P921

Q28364060-4185BA58-66EA-4351-9994-BD94DD8B6B95

P932

Q28364060-AB4446FE-1775-4001-A856-3F1E6DD08364

P3181

P356

P1433

The EMBO Journal

P1476

Activation of Cdh1-dependent A ...... checkpoint in vertebrate cells

@en

P2093

H Saya

http://www.w3.org/2001/XMLSchema#string

M Nakao

http://www.w3.org/2001/XMLSchema#string

S Kotani

http://www.w3.org/2001/XMLSchema#string

T Sudo

http://www.w3.org/2001/XMLSchema#string

Y Ota

http://www.w3.org/2001/XMLSchema#string

Y Takami

http://www.w3.org/2001/XMLSchema#string

P2860

Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

Nuclear localization of cyclin B1 controls mitotic entry after DNA damage

Regulation of APC activity by phosphorylation and regulatory factors

APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle.

P304

6499-508

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1524649

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/EMBOJ/20.22.6499

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P50

Shunichi Takeda

P577

2001-11-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11648397

http://www.w3.org/2001/XMLSchema#string

P698

11707420

http://www.w3.org/2001/XMLSchema#string

P921

P932

125730

http://www.w3.org/2001/XMLSchema#string