CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
about
Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1Identification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH-based screenAn overview of Cdk1-controlled targets and processesThe function of APC/CCdh1 in cell cycle and beyondDirect interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1Reverse engineering of the spindle assembly checkpointHuman BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCInhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1MAD2B is an inhibitor of the anaphase-promoting complexAPC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complexGamma-secretase activating protein is a therapeutic target for Alzheimer's diseaseEmi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitorThe tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complexThe human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinaseIdentification of a MAD2-binding protein, CMT2, and its role in mitosis.Identification of a physiological E2 module for the human anaphase-promoting complexDifferential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes.Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exitAn architectural map of the anaphase-promoting complexSecurin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesisAnalysis of a generic model of eukaryotic cell-cycle regulationLesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiaeThe products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein familyCheckpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complexIdentification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulationNonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosisDistinct subcellular localization patterns contribute to functional specificity of the Cln2 and Cln3 cyclins of Saccharomyces cerevisiaeCdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiaeLoss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damageIntegrative analysis of cell cycle control in budding yeastThe checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiationCdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1Mammalian Cdh1/Fzr mediates its own degradationCdc20 associates with the kinase aurora2/AikCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Mechanisms and regulation of the degradation of cyclin BSpindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activityMad2 transiently associates with an APC/p55Cdc complex during mitosis
P2860
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P2860
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@ast
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@en
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@nl
type
label
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@ast
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@en
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@nl
prefLabel
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@ast
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@en
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@nl
P3181
P1433
P1476
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
@en
P2093
P3181
P356
10.1126/SCIENCE.278.5337.460
P407
P577
1997-10-17T00:00:00Z