Modulation of GABA(A) receptor channel gating by pentobarbital
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Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABAMolecular mechanisms of antiseizure drug activity at GABAA receptorsSpike Timing Rigidity Is Maintained in Bursting Neurons under Pentobarbital-Induced Anesthetic Conditions.Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.The activation mechanism of alpha1beta2gamma2S and alpha3beta3gamma2S GABAA receptors.Mutations in the main cytoplasmic loop of the GABA(A) receptor α4 and δ subunits have opposite effects on surface expression.Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids.Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currentsAllosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor.Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye.Pharmacology of structural changes at the GABA(A) receptor transmitter binding site.Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels.Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital.Synaptic-type α1β2γ2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs.Exploring new pharmacology and toxicological screening and safety evaluation of one widely used formulation of Nidrakar Bati from South Asia region.Sedative and Hypnotic Activities of the Methanolic and Aqueous Extracts of Lavandula officinalis from MoroccoIntroduced Amino Terminal Epitopes Can Reduce Surface Expression of Neuronal Nicotinic Receptors.Agonist-specific conformational changes in the α1-γ2 subunit interface of the GABA A receptor.Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetateComparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABA(A) Receptors.Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.Photo-activated azi-etomidate, a general anesthetic photolabel, irreversibly enhances gating and desensitization of gamma-aminobutyric acid type A receptors.The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat alpha1beta2gamma2L GABA(A) receptor.Steroid interaction with a single potentiating site is sufficient to modulate GABA-A receptor function.Single-channel analysis of ethanol enhancement of glycine receptor functionMutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids.Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant.Number and locations of agonist binding sites required to activate homomeric Cys-loop receptorsThe benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA(A) receptor is not obligatory for channel potentiation.General anesthetic actions on GABA(A) receptors.Insights into the structure and pharmacology of GABA(A) receptors.Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.The actions of drug combinations on the GABAA receptor manifest as curvilinear isoboles of additivity.Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.Inverse effects on gating and modulation caused by a mutation in the M2-M3 Linker of the GABA(A) receptor gamma subunit.Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells.Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptorsThe pre-M1 segment of the alpha1 subunit is a transduction element in the activation of the GABAA receptor.
P2860
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P2860
Modulation of GABA(A) receptor channel gating by pentobarbital
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Modulation of GABA(A) receptor channel gating by pentobarbital
@ast
Modulation of GABA(A) receptor channel gating by pentobarbital
@en
Modulation of GABA(A) receptor channel gating by pentobarbital
@nl
type
label
Modulation of GABA(A) receptor channel gating by pentobarbital
@ast
Modulation of GABA(A) receptor channel gating by pentobarbital
@en
Modulation of GABA(A) receptor channel gating by pentobarbital
@nl
prefLabel
Modulation of GABA(A) receptor channel gating by pentobarbital
@ast
Modulation of GABA(A) receptor channel gating by pentobarbital
@en
Modulation of GABA(A) receptor channel gating by pentobarbital
@nl
P2860
P3181
P1476
Modulation of GABA(A) receptor channel gating by pentobarbital
@en
P2093
P2860
P304
P3181
P356
10.1111/J.1469-7793.2001.00715.X
10.1113/JPHYSIOL.2001.012818
P407
P577
2001-12-15T00:00:00Z