Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth
about
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administrationscVEGF microbubble ultrasound contrast agents: a novel probe for ultrasound molecular imaging of tumor angiogenesis.Modulating tumor vasculature through signaling inhibition to improve cytotoxic therapy.The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.Scheduling of radiation with angiogenesis inhibitors anginex and Avastin improves therapeutic outcome via vessel normalization.BMS-690514, a VEGFR and EGFR tyrosine kinase inhibitor, shows anti-tumoural activity on non-small-cell lung cancer xenografts and induces sequence-dependent synergistic effect with radiation.Antiangiogenic agents targeting vascular endothelial growth factor and its receptors in clinical development.Therapies directed at vascular endothelial growth factor.Advances in molecular therapies in patients with brain tumors.A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies.HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cellsAutocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth.Cellular responses to EGFR inhibitors and their relevance to cancer therapy.Effects of androgen suppression and radiation on prostate cancer suggest a role for angiogenesis blockade.Inhibition of vascular endothelial growth factor A and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculatureNovel therapeutics in adult malignant brain gliomas.Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude miceAntiangiogenic therapy in human gastrointestinal malignancies.Correlation between the tumoral expression of beta3-integrin and outcome in cervical cancer patients who had undergone radiotherapyVatalanib: the clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours.Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiationAntiangiogenic effects of noscapine enhance radioresponse for GL261 tumors.Combining molecular targeted agents with radiation therapy for malignant gliomasAutotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell LinesSurvival of the fittest: cancer stem cells in therapeutic resistance and angiogenesisAntiangiogenics and radiotherapy.Angiogenesis as a therapeutic target in malignant gliomas.Modulating the tumor microenvironment to increase radiation responsiveness.The cancer stem cell microenvironment and anti-cancer therapy.Microenvironment and radiation therapyRecombinant mistletoe lectin induces p53-independent apoptosis in tumour cells and cooperates with ionising radiation.Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.Statins Enhance Expression of Growth Factors and Activate the PI3K/Akt-mediated Signaling Pathway after Experimental Intracerebral Hemorrhage.Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice.An Experimental Study of Radiation Effect on Normal Tissue: Analysis of HIF-1α, VEGF, eIF2, TIA-1, and TSP-1 ExpressionRadiotherapy in combination with vascular-targeted therapies.Unexpected late radiation neurotoxicity following bevacizumab use: a case series.Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells.Inhibition of vascular endothelial growth factor signalling using cediranib (RECENTIN; AZD2171) enhances radiation response and causes substantial physiological changes in lung tumour xenografts.The prognostic significance of growth factors and growth factor receptors in gastric adenocarcinoma.
P2860
Q28378001-1DE21331-291E-46A8-8A95-37391A16FA71Q30425448-6B25D9B7-DD8A-4584-962A-035A41C2D2CFQ33733303-40DB0FF2-FD2E-4EED-AFEB-1A9744596E1EQ34011118-F137D552-EC57-4FD0-85FB-CB685AB7816DQ34039409-E4FD6522-EE0F-4426-ABE6-6764C91B4941Q34059649-D99F4172-FD6B-4E69-8C5C-67BEA4683A83Q34974876-B6D04EFA-A057-4835-8B1C-B3227F1B0161Q35011885-C1147A3A-BF58-434A-B153-73A0001ED178Q35113656-8C5E6835-116B-42AA-A24E-824D140C6AA9Q35207344-7AA8825D-93EE-4FC7-85DC-E7739182A944Q35249827-C4505819-C528-4E94-BF38-8D05F5E4FDF5Q35826030-0149595E-F0F2-4965-8463-9C6F3A5DF7D4Q36003118-92FAA8A4-D637-43EB-92BA-4F64C003D8D5Q36005858-3C7390D5-9E74-4029-AFC1-034E31C4BD75Q36027155-3540D797-0439-471E-805A-414988F13489Q36187046-5DC4F2CA-B033-4F73-8C5B-880C34794857Q36259629-11472DED-3B25-4D4F-8F06-A125F0C8B3FFQ36591067-181C4525-45FF-4776-996E-8B6138A80E7AQ36615716-B8AFB325-0FF7-40EE-A7B2-9F44BEB97478Q36736364-606F3113-DCFE-4C8E-80DB-18A6E6804954Q36891571-75B09D6F-6AF7-4AA4-997E-0E843CA26C81Q36947173-A26E28C8-81F3-40C3-AC0B-FE4289A03444Q37099594-47D869E9-EDF4-4264-A3AC-AD938816DCD2Q37177631-A6BC1228-7211-4285-8970-B001C1598564Q37186425-93B2C3D8-36D9-4572-959D-209C55AF1415Q37222791-9DEA86CE-29A9-444E-81FB-6094022D623AQ37504362-2D40B652-A589-471B-BB2E-BE8674F755D1Q37613364-840B9597-2E90-4310-9473-1B2F56FA82EEQ37628729-839C04E9-1CB2-44E8-A143-CCC8D8A3ADF2Q38091084-9CFF4ED7-E756-4208-8F8A-AC47765BA05BQ38309612-7B4F19DF-994C-4E04-8AE1-06BAC4EF9F71Q38341425-82174D4B-BEB9-40FC-A74F-8F435190D3EAQ41544765-CAA3858B-8F6B-4129-8E7D-3760CC9DDC3DQ41902466-7877CE0D-D483-435C-97B4-EE73764E59A1Q41906420-D917FF23-B010-4C4D-84AB-4E979925B0D0Q42203737-4264375B-C0D4-4290-8C7C-D72C1B122E82Q43446900-18272CE9-BB27-45D0-88F1-5F34FC97BE29Q44830447-17495D92-907D-4113-9626-9A165C052B2FQ46344533-6BE1DBE9-ED6C-4DA5-8D1D-24BD34306FC3Q53358684-F6146AF6-CEE4-48FE-A05B-EDC1607DE229
P2860
Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@ast
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@en
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@nl
type
label
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@ast
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@en
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@nl
prefLabel
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@ast
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@en
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@nl
P2093
P2860
P356
P1476
Effect of VEGF receptor inhibi ...... helial cells and tumour growth
@en
P2093
Glanzmann C
P2860
P2888
P304
P356
10.1054/BJOC.2001.2166
P407
P577
2001-12-01T00:00:00Z
P5875
P6179
1004688455