Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design
about
Shikimic acid: review of its analytical, isolation, and purification techniques from plant and microbial sourcesAn unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzymeStructure of Insoluble Rat Sperm Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) via Heterotetramer Formation with Escherichia coli GAPDH Reveals Target for Contraceptive DesignA critical review on Chagas disease chemotherapyThe N'-terminal domain of glyceraldehyde-3-phosphate dehydrogenase of the apicomplexan Plasmodium falciparum mediates GTPase Rab2-dependent recruitment to membranesWanted: unique names for unique atom positions. PDB-wide analysis of diastereotopic atom names of small molecules containing diphosphate.2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.Proteome scale comparative modeling for conserved drug and vaccine targets identification in Corynebacterium pseudotuberculosisPurine and pyrimidine transport in pathogenic protozoa: from biology to therapy.Anticancer agents that counteract tumor glycolysis.Trypanosoma brucei adenine-phosphoribosyltransferases mediate adenine salvage and aminopurinol susceptibility but not adenine toxicity.Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.A structurally conserved water molecule in Rossmann dinucleotide-binding domains.Pattern recognition techniques applied to the study of leishmanial glyceraldehyde-3-phosphate dehydrogenase inhibition.Computational Methods Applied to Rational Drug Design.Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors.A pharmacophore-based virtual screening approach for the discovery of Trypanosoma cruzi GAPDH inhibitors.Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the Gram-Positive Bacterial Pathogen A. vaginae, an Immunoevasive Factor that Interacts with the Human C5a Anaphylatoxin.Synthesis of 2'-([1,2,3]triazol-1-yl)-2'-deoxyadenosines.Identification of electronic and structural descriptors of adenosine analogues related to inhibition of leishmanial glyceraldehyde-3-phosphate dehydrogenase.D-Glyceraldehyde-3-Phosphate Dehydrogenase Structure and Function.
P2860
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P2860
Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Adenosine analogues as selecti ...... ia structure-based drug design
@ast
Adenosine analogues as selecti ...... ia structure-based drug design
@en
Adenosine analogues as selecti ...... ia structure-based drug design
@nl
type
label
Adenosine analogues as selecti ...... ia structure-based drug design
@ast
Adenosine analogues as selecti ...... ia structure-based drug design
@en
Adenosine analogues as selecti ...... ia structure-based drug design
@nl
prefLabel
Adenosine analogues as selecti ...... ia structure-based drug design
@ast
Adenosine analogues as selecti ...... ia structure-based drug design
@en
Adenosine analogues as selecti ...... ia structure-based drug design
@nl
P2093
P2860
P3181
P356
P1476
Adenosine analogues as selecti ...... ia structure-based drug design
@en
P2093
A M Aronov
C L Verlinde
F S Buckner
J C Bressi
L N Nguyen
P2860
P304
P3181
P356
10.1021/JM000472O
P407
P577
2001-06-21T00:00:00Z