Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms. - Wikidata - wikimedia - TriplyDB

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

http://www.wikidata.org/entity/Q35539852

about

The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!Assembling the components of the quorum sensing pathway in African trypanosomes Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells Metabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathway Regulators of Trypanosoma brucei cell cycle progression and differentiation identified using a kinome-wide RNAi screen Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels Epac signaling is required for hippocampus-dependent memory retrieval.Reactivation of flagellar motility in demembranated Leishmania reveals role of cAMP in flagellar wave reversal to ciliary waveform Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses cAMP analogs and their metabolites enhance TREK-1 mRNA and K+ current expression in adrenocortical cells.ACTH induces Cav3.2 current and mRNA by cAMP-dependent and cAMP-independent mechanisms.Calflagin inhibition prolongs host survival and suppresses parasitemia in Trypanosoma brucei infection.β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent.Cellular and molecular remodeling of the endocytic pathway during differentiation of Trypanosoma brucei bloodstream forms.Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.The cell biology of Trypanosoma brucei differentiation.Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA Independent pathways can transduce the life-cycle differentiation signal in Trypanosoma brucei.Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes.Cyclic AMP Regulates Social Behavior in African Trypanosomes.How do trypanosomes change gene expression in response to the environment?Cancer in the parasitic protozoans Trypanosoma brucei and Toxoplasma gondii.Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei.A short bifunctional element operates to positively or negatively regulate ESAG9 expression in different developmental forms of Trypanosoma brucei Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.The AMPKα1 Pathway Positively Regulates the Developmental Transition from Proliferation to Quiescence in Trypanosoma brucei.An Overview of Trypanosoma brucei Infections: An Intense Host-Parasite Interaction.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.New discoveries in the transmission biology of sleeping sickness parasites: applying the basics.Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.Epac proteins: specific ligands and role in cardiac remodelling.cAMP signalling in trypanosomatids: role in pathogenesis and as a drug target.The Cytological Events and Molecular Control of Life Cycle Development of Trypanosoma brucei in the Mammalian Bloodstream.Inhibition of the equilibrative nucleoside transporter 1 and activation of A2A adenosine receptors by 8-(4-chlorophenylthio)-modified cAMP analogs and their hydrolytic products.PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.Prostaglandin E2 activates Rap1 via EP2/EP4 receptors and cAMP-signaling in rheumatoid synovial fibroblasts: involvement of Epac1 and PKA.Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.Interspecies quorum sensing in co-infections can manipulate trypanosome transmission potential.

P2860

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P2860

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

http://www.wikidata.org/entity/Q35539852

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2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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Proceedings of the National Academy of Sciences of the United States of America

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Hydrolysis products of cAMP an ...... m slender to stumpy-like forms

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Aaron Riechers

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Frank Schwede

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Joseph A Beavo

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Martin Sadilek

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P2860

Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.

The developmental cell biology of Trypanosoma brucei

Role of the long slender to short stumpy transition in the life cycle of the african trypanosomes

"Rapid-impact interventions": how a policy of integrated control for Africa's neglected tropical diseases could benefit the poor

Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.

Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNA interference library.

Cyclic AMP signaling in trypanosomatids.

The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei

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Trypanosoma brucei

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