Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine - Wikidata - wikimedia - TriplyDB

Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine

Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine

http://www.wikidata.org/entity/Q28367438

about

New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids Cross-resistance testing of antihepadnaviral compounds using novel recombinant baculoviruses which encode drug-resistant strains of hepatitis B virus Anti-hepatitis B virus activity and metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine.Phosphorothioate di- and trinucleotides as a novel class of anti-hepatitis B virus agents.Preclinical aspects of lamivudine and famciclovir against hepatitis B virus.Development of resistance and perspectives for future therapies against hepatitis B infections: lessons to be learned from HIV.The enantioselectivity of enzymes involved in current antiviral therapy using nucleoside analogues: a new strategy?Characterization of the antiviral effect of 2',3'-dideoxy-2', 3'-didehydro-beta-L-5-fluorocytidine in the duck hepatitis B virus infection model.Treatment of chronic hepatitis B: new antiviral therapies.Importance of serum concentration of adefovir for Lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B.Hepatitis B virus genotyping among chronic hepatitis B individuals with resistance to Lamivudine in shahrekord, iran.Mutations of the woodchuck hepatitis virus polymerase gene that confer resistance to lamivudine and 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil.Quantitative detection of single base mutation by combining PNA hybridization and MALDI-TOF mass analysis.Comparison of anti-hepatitis B virus activities of lamivudine and clevudine by a quantitative assay.Generation of stable cell lines expressing Lamivudine-resistant hepatitis B virus for antiviral-compound screening.Emerging therapies of hepatitis B and C.Generation of duck hepatitis B virus polymerase mutants through site-directed mutagenesis which demonstrate resistance to lamivudine [(--)-beta-L-2', 3'-dideoxy-3'-thiacytidine] in vitro Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: a randomised trial.Current Antiviral Therapy of Chronic Hepatitis B: Efficacy and Safety Response to long-term lamivudine treatment (up to 5 years) in patients with severe chronic hepatitis B, role of genotype and drug resistance.Drug insight: Nucleoside and nucleotide analog inhibitors for hepatitis B.Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus.Targets of emerging therapies for viral hepatitis B and C.Viral dynamics in hepatitis B virus infection.Molecular mechanisms underlying HBsAg negativity in occult HBV infection.Mutations outside the YMDD motif in the P protein can also cause DHBV resistant to Lamivudine.Line probe assay for monitoring drug resistance in hepatitis B virus-infected patients during antiviral therapy.Monitoring the emergence of hepatitis B virus polymerase gene variants during lamivudine therapy using the LightCycler.In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir.Modulation of the metabolism of beta-L-(-)-2',3'-dideoxy-3'-thiacytidine by thymidine, fludarabine, and nitrobenzylthioinosine.Pyrosequencing for detection of lamivudine-resistant hepatitis B virus.Computational model of hepatitis B virus DNA polymerase: molecular dynamics and docking to understand resistant mutations.Review: Present and future directions in the treatment of chronic hepatitis B infection.In vitro anti-human immunodeficiency virus and anti-hepatitis B virus activities and pharmacokinetic properties of heterodinucleoside phosphates containing AZT or ddC.Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase.The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.Dynamics of hepatitis B virus resistance to lamivudine.Zinc finger proteins designed to specifically target duck hepatitis B virus covalently closed circular DNA inhibit viral transcription in tissue culture.Inhibitory effect of a nucleotide analog on infectious salmon anemia virus infection.

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Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine

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1995 nî lūn-bûn

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1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1995 թվականի հուլիսին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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Antimicrobial Agents and Chemotherapy

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Mechanism of inhibition of duc ...... -2',3'-dideoxy-3'-thiacytidine

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A Severini

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D L Tyrrell

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J S Wilson

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X Y Liu

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P2860

(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma

The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro

Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues

Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5-methyldeoxycytidines and of other nucleoside analogs

Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs

The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase

Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P--N--P linkage.

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