Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis - Wikidata - wikimedia - TriplyDB

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

http://www.wikidata.org/entity/Q28367890

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Comparison of the echinocandin caspofungin with amphotericin B for treatment of histoplasmosis following pulmonary challenge in a murine model In vitro susceptibility testing methods for caspofungin against Aspergillus and Fusarium isolates In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373 Antifungal peptides: novel therapeutic compounds against emerging pathogens In vitro activities of semisynthetic pneumocandin L-733,560 against fluconazole-resistant and -susceptible Candida albicans isolates In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis Treatment of histoplasmosis with MK-991 (L-743,872)The 1998 Garrod lecture. Current and future antifungal therapy: new targets for antifungal agents.Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate.Antifungal peptides: potential candidates for the treatment of fungal infections.Pneumocandin L-743,872 enhances the activities of amphotericin B and fluconazole against Cryptococcus neoformans in vitro Treatment of murine Candida krusei or Candida glabrata infection with L-743,872 Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872).Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors.Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies.Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival.Discovery and development of first in class antifungal caspofungin (CANCIDAS®)--a case study.Clinical pharmacokinetics of inhaled antimicrobials.Geranylgeranyltransferase I of Candida albicans: null mutants or enzyme inhibitors produce unexpected phenotypes.Activities of an intravenous formulation of itraconazole in experimental disseminated Aspergillus, Candida, and Cryptococcus infections.Aerosol and parenteral pneumocandins are effective in a rat model of pulmonary aspergillosis.Isolation of a gene involved in 1,3-beta-glucan synthesis in Aspergillus nidulans and purification of the corresponding protein.Temporal events in the intravenous challenge model for experimental Candida albicans infections in female mice.Inactivation of Kex2p diminishes the virulence of Candida albicans.Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase.Direct comparison of the pharmacodynamics of four antifungal drugs in a mouse model of disseminated candidiasis using microbiological assays of serum drug concentrations.Creation, characterization and utilization of Cryptococcus neoformans mutants sensitive to micafungin.

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P2860

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

http://www.wikidata.org/entity/Q28367890

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1995 nî lūn-bûn

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1995 թուականի Մայիսին հրատարակուած գիտական յօդուած

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P2860

In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin

In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373

Amphotericin B: 30 years of clinical experience.

Synthesis and antifungal activity of novel cationic pneumocandin B(o) derivatives.

Systemically administered antifungal agents. A review of their clinical pharmacology and therapeutic applications.

Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis

Use of DBA/2N mice in models of systemic candidiasis and pulmonary and systemic aspergillosis

Resistant fits for some commonly used logistic models with medical application.

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