Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands - Wikidata - wikimedia - TriplyDB

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

http://www.wikidata.org/entity/Q28369113

about

Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate Significance of ligand tails for interaction with the minor groove of B-DNA Inhibition of melanogenesis by the pyridinyl imidazole class of compounds: possible involvement of the Wnt/β-catenin signaling pathway Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines Activation of gene expression by small molecule transcription factors Chemical approaches to control gene expression.Use of fluorescent sequence-specific polyamides to discriminate human chromosomes by microscopy and flow cytometry.Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture.Improved nuclear localization of DNA-binding polyamides.Completion of a Programmable DNA-Binding Small Molecule Library Discovery of inhibitors of aberrant gene transcription from Libraries of DNA binding molecules: inhibition of LEF-1-mediated gene transcription and oncogenic transformation.Binding of Hoechst 33258 and its derivatives to DNA.Telomerase. A target for anticancer therapy.DNA sequence recognition in the minor groove by crosslinked polyamides: The effect of N-terminal head group and linker length on binding affinity and specificity Drug-DNA recognition: energetics and implications for design.Dimeric calixarenes: a new family of major-groove binders.Promoter scanning for transcription inhibition with DNA-binding polyamides.Triplex-forming molecules: from concepts to applications.Inhibition of human papilloma virus E2 DNA binding protein by covalently linked polyamides.An approach to gene-specific transcription inhibition using oligonucleotides complementary to the template strand of the open complex.On the kinetics of distamycin binding to its target sites on duplex DNA.Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)Chemicals that footprint DNA: hitting HIV-1 in the minor groove Effects of anticancer drugs on transcription factor-DNA interactions.Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.Covalent capture: merging covalent and noncovalent synthesis.RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.Programmable DNA-binding small molecules.Effect of ligand sequence-specific modification on DNA hybrid catalysis.Binding of bis-linked netropsin derivatives in the parallel-stranded hairpin form to DNA.Complex of the herpes simplex virus type 1 origin binding protein UL9 with DNA as a platform for the design of a new type of antiviral drugs.Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multidrug resistant (MDR1) gene.Influence of netropsin's charges on the minor groove width of d(CGCGAATTCGCG)2.Specific down-regulation of an engineered human cyclin D1 promoter by a novel DNA-binding ligand in intact cells.Sequence-specific protection of plasmid DNA from restriction endonuclease hydrolysis by pyrrole-imidazole-cyclopropapyrroloindole conjugates.Synthesis of lipid derivatives of pyrrole polyamide and their biological activity.

P2860

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P2860

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

http://www.wikidata.org/entity/Q28369113

description

1998 nî lūn-bûn

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1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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type

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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Proceedings of the National Academy of Sciences of the United States of America

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Inhibition of RNA polymerase I ...... synthetic DNA-binding ligands

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D E Mosier

http://www.w3.org/2001/XMLSchema#string

E E Baird

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J M Gottesfeld

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J W Trauger

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L A Dickinson

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P B Dervan

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R J Gulizia

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P2860

Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro

Solution structure of the ETS domain from murine Ets-1: a winged helix-turn-helix DNA binding motif

Structural basis for DNA bending by the architectural transcription factor LEF-1

Crystal structure of a yeast TBP/TATA-box complex

Co-crystal structure of TBP recognizing the minor groove of a TATA element

A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex

Structural basis for G.C recognition in the DNA minor groove

The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA

Regulation of gene expression by small molecules

Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands

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95

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9789010

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