Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture.
about
Antitumor activity of a pyrrole-imidazole polyamideStructural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor BindingImproved nuclear localization of DNA-binding polyamides.Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cellsCompletion of a Programmable DNA-Binding Small Molecule LibraryRational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides.Binding studies of a large antiviral polyamide to a natural HPV sequence.Pretranscriptional regulation of Tgf-beta1 by PI polyamide prevents scarring and accelerates wound healing of the cornea after exposure to alkali.HPV episome levels are potently decreased by pyrrole-imidazole polyamides.The subcellular distribution of small molecules: a meta-analysis.Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes.Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Synthesis of cyclic Py-Im polyamide libraries.DNA sequence selectivity of hairpin polyamide turn unitsDNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia.Hoechst tagging: a modular strategy to design synthetic fluorescent probes for live-cell nucleus imaging.Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA.Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.Naphthyridine tetramer with a pre-organized structure for 1:1 binding to a CGG/CGG sequence.Chemical approaches to the discovery and development of cancer therapies.Alpha-diaminobutyric acid-linked hairpin polyamides.Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.Activity of a Py-Im polyamide targeted to the estrogen response element.In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography.The reach of linear protein-DNA dimerizers.Cyclic pyrrole-imidazole polyamides targeted to the androgen response element.Solution-phase synthesis of pyrrole-imidazole polyamidesAnimal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit.Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studiesOligomerization route to Py-Im polyamide macrocycles.Covalent capture: merging covalent and noncovalent synthesis.Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.Approaches to target the genome and its epigenome in cancer.
P2860
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P2860
Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture.
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@ast
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@en
type
label
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@ast
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@en
prefLabel
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@ast
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@en
P2093
P2860
P356
P1476
Nuclear localization of pyrrol ...... in conjugates in cell culture.
@en
P2093
Benjamin S Edelson
Nicholas G Nickols
Timothy P Best
P2860
P304
12063-12068
P356
10.1073/PNAS.2035074100
P407
P50
P577
2003-09-30T00:00:00Z