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Antiviral nucleoside drug delivery via amino acid phosphoramidates

Antiviral nucleoside drug delivery via amino acid phosphoramidates

http://www.wikidata.org/entity/Q28370086

about

Synthesis of nucleoside phosphate and phosphonate prodrugs Synthesis and antiviral activity of amino acid carbamate derivatives of AZT Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation Comparison of the antiviral activity of hydrophobic amino acid phosphoramidate monoesters of 2'3'-dideoxyadenosine (DDA) and 3'-azido-3'-deoxythymidine (AZT).Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides.Pharmacokinetics of amino acid phosphoramidate monoesters of zidovudine in rats Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target.Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation.Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation.Monitoring the intracellular metabolism of nucleoside phosphoramidate pronucleotides by 31P NMR.Synthesis and anti-herpetic activity of phosphoramidate ProTides.Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates.A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.

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P2860

Antiviral nucleoside drug delivery via amino acid phosphoramidates

http://www.wikidata.org/entity/Q28370086

description

1999 nî lūn-bûn

@nan

1999 թուականին հրատարակուած գիտական յօդուած

@hyw

1999 թվականին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@ast

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@en

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@nl

type

label

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@ast

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@en

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@nl

prefLabel

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@ast

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@en

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@nl

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15257779908041599

P1433

Nucleosides & nucleotides

P1476

Antiviral nucleoside drug delivery via amino acid phosphoramidates

@en

P2093

C L Zimmerman

http://www.w3.org/2001/XMLSchema#string

C R Wagner

http://www.w3.org/2001/XMLSchema#string

E J McIntee

http://www.w3.org/2001/XMLSchema#string

G W Griesgraber

http://www.w3.org/2001/XMLSchema#string

H Song

http://www.w3.org/2001/XMLSchema#string

S L Chang

http://www.w3.org/2001/XMLSchema#string

P2860

Synthesis and biological activity of aromatic amino acid phosphoramidates of 5-fluoro-2'-deoxyuridine and 1-beta-arabinofuranosylcytosine: evidence of phosphoramidase activity.

Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs.

Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.

The use of viral culture and p24 antigen testing to diagnose human immunodeficiency virus infection in neonates. The HIV Infection in Newborns French Collaborative Study Group.

P304

913-9

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scholarly article

P356

10.1080/15257779908041599

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P407

P433

4-5

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18

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1999-01-01T00:00:00Z

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10432709

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