Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation.
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Targeting translation initiation in breast cancerA capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma.eIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells.Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitorsDual modulation of Ras-Mnk and PI3K-AKT-mTOR pathways: A Novel c-FLIP inhibitory mechanism of 3-AWA mediated translational attenuation through dephosphorylation of eIF4E.Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation.Potential therapeutic applications of RNA cap analogs.Targeting translation: eIF4E as an emerging anticancer drug target.Translational control of the fibroblast-extracellular matrix association: An application to pulmonary fibrosis.Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells.Targeting of protein translation as a new treatment paradigm for prostate cancer.Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in miceInternal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds.Resistance to EGFR-TKI can be mediated through multiple signaling pathways converging upon cap-dependent translation in EGFR-wild type NSCLC.4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma.Elevated levels of p-Mnk1, p-eIF4E and p-p70S6K proteins are associated with tumor recurrence and poor prognosis in astrocytomas.Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5'UTR and PI3K Signaling.
P2860
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P2860
Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Attacking a nexus of the oncog ...... nt eIF4F-mediated translation.
@en
type
label
Attacking a nexus of the oncog ...... nt eIF4F-mediated translation.
@en
prefLabel
Attacking a nexus of the oncog ...... nt eIF4F-mediated translation.
@en
P2860
P1476
Attacking a nexus of the oncog ...... nt eIF4F-mediated translation.
@en
P2093
Peter B Bitterman
Vitaly A Polunovsky
P2860
P304
P356
10.1158/1535-7163.MCT-11-0530
P577
2012-05-01T00:00:00Z