Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells
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HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapyDirect interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growthA new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondriaNegative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stressMitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epitheliumGlutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cellsASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interactionCytotoxicity of Vinca minorIRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumorsSelective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell linesMEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption.Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells.Microtubules and their role in cellular stress in cancerInvestigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo.CD40 activation in epithelial ovarian carcinoma cells modulates growth, apoptosis, and cytokine secretion.Paclitaxel-induced cell death: where the cell cycle and apoptosis come together.BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell deathRole of cyclin B1/Cdc2 up-regulation in the development of mitotic prometaphase arrest in human breast cancer cells treated with nocodazole2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.Stress-induced phosphoprotein 1 as a secreted biomarker for human ovarian cancer promotes cancer cell proliferationGamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways.Review: tubulin function, action of antitubulin drugs, and new drug development.MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosisAlternative signaling pathways: when, where and why?Involvement of JNK-mediated pathway in EGF-mediated protection against paclitaxel-induced apoptosis in SiHa human cervical cancer cells.MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer.Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol.ASK1 regulates cardiomyocyte death but not hypertrophy in transgenic miceMalate dehydrogenase 2 confers docetaxel resistance via regulations of JNK signaling and oxidative metabolism.Cell cycle modulatory and apoptotic effects of plant-derived anticancer drugs in clinical use or development.Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine.Microtubule destabilising agents: far more than just antimitotic anticancer drugs.CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity.RanBP1 downregulation sensitizes cancer cells to taxol in a caspase-3-dependent manner.Erythropoietin treatment of human ovarian cancer cells results in enhanced signaling and a paclitaxel-resistant phenotype.Ochratoxin A: apoptosis and aberrant exit from mitosis due to perturbation of microtubule dynamics?Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro.Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells.
P2860
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P2860
Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Microtubule dysfunction induce ...... thways in ovarian cancer cells
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Microtubule dysfunction induce ...... thways in ovarian cancer cells
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Microtubule dysfunction induce ...... thways in ovarian cancer cells
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type
label
Microtubule dysfunction induce ...... thways in ovarian cancer cells
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Microtubule dysfunction induce ...... thways in ovarian cancer cells
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Microtubule dysfunction induce ...... thways in ovarian cancer cells
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prefLabel
Microtubule dysfunction induce ...... thways in ovarian cancer cells
@ast
Microtubule dysfunction induce ...... thways in ovarian cancer cells
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Microtubule dysfunction induce ...... thways in ovarian cancer cells
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P2093
P2860
P3181
P356
P1476
Microtubule dysfunction induce ...... thways in ovarian cancer cells
@en
P2093
D C Henley
J Wimalasena
P2860
P304
P3181
P356
10.1074/JBC.274.12.8208
P407
P577
1999-03-19T00:00:00Z