A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro
about
Gene and protein expression and cellular localisation of cytochrome P450 enzymes of the 1A, 2A, 2C, 2D and 2E subfamilies in equine intestine and liver.The influence of hormones and pharmaceutical agents on DHEA and DHEA-S concentrations: a review of clinical studies.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.In vitro tests for predicting drug-drug interactions: the need for validated procedures.Transcriptional regulation of the human pregnane-X receptor.Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.Genotype-guided tacrolimus dosing in African-American kidney transplant recipients.Drugs as CYP3A probes, inducers, and inhibitors.Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction.Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.Upgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing.Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage.Automated triplexed hepatocyte-based viability and CYP1A and -3A induction assays.Determination of CYP3A4 Inducing Properties of Compounds Using a Laboratory-Developed Cell-Based Assay.Differential gene expression of CYP3A isoforms in equine liver and intestines.
P2860
Q34318422-85594CA0-3C96-4631-98B7-3421C48F4FCAQ34544099-DCC5EFDB-BDA6-4E66-A665-78C2081DE939Q34604457-111F03F7-4399-4418-B257-48FA462C1504Q35060620-902440B1-C79F-4BEA-98C3-199BB570E498Q36473472-A4FF3B54-B6AD-4E2C-8F77-2F8F11E18BADQ36546250-CAD9AB8A-8829-41E2-943E-A20056607917Q36551142-28366021-024D-4198-8EB8-7CB268B6ACFAQ37009025-3193127E-8909-45C3-881B-6AB03C37F2AAQ37023996-C68F9501-0E88-4ACA-A893-1DD8E66042BCQ37756178-8CCF1FFE-0B08-49E9-9F46-EB9EC407ED58Q38180822-F39CB3AD-2F07-4EB8-B366-DD44BA68A108Q38294142-1B63C011-42E2-4557-A8F9-D2C7EA4B5A77Q38743580-0E0E4358-73DE-4428-A455-5370F94EDC70Q43064767-E6B530AA-62CB-455C-8950-1DBC62864468Q43268652-1CC91A4A-D219-4E10-AF86-6BC000EEA8D1Q45930411-40B25055-ABC7-4E66-9DEA-48ABFED221EFQ50249231-B7ECEEE3-F0CA-42A0-8119-3DDBFDC34EF9Q53189497-BF73A939-6E0E-4ED6-B1D3-D69C24735087
P2860
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@ast
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@en
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@nl
type
label
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@ast
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@en
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@nl
prefLabel
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@ast
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@en
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@nl
P2093
P2860
P356
P1433
P1476
A reporter gene assay to asses ...... the human CYP3A4 gene in vitro
@en
P2093
P2860
P304
P356
10.1080/004982599238669
P407
P577
1999-03-01T00:00:00Z