Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.
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The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammalsCalcitriol in Combination Therapy for Prostate Cancer: Pharmacokinetic and Pharmacodynamic InteractionsStem Cell Strategies to Evaluate Idiosyncratic Drug-induced Liver InjuryDehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptorDexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrierPanobinostat PK/PD profile in combination with bortezomib and dexamethasone in patients with relapsed and relapsed/refractory multiple myelomaCombined effect of regulatory polymorphisms on transcription of UGT1A1 as a cause of Gilbert syndrome.Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.Explaining variability in ciclosporin exposure in adult kidney transplant recipients.Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver.Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium FerulateInduction of CYP3A4 by vinblastine: Role of the nuclear receptor NR1I2GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression.CAR and PXR: the xenobiotic-sensing receptors.Influence of SLCO1B3 haplotype-tag SNPs on docetaxel disposition in Chinese nasopharyngeal cancer patients.Breast cancer-resistance protein (BCRP1) in the fetal mouse brain: development and glucocorticoid regulation.Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR).Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons.Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance.PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.RBCK1, an E3 ubiquitin ligase, interacts with and ubiquinates the human pregnane X receptor.Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.RETRACTED: CYP2D6 Is Inducible by Endogenous and Exogenous CorticosteroidsAltered drug metabolism during pregnancy: hormonal regulation of drug-metabolizing enzymesConstitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1.Drugs as CYP3A probes, inducers, and inhibitors.Opposite Effects of Single-Dose and Multidose Administration of the Ethanol Extract of Danshen on CYP3A in Healthy Volunteers.Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway.Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cellsLong-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells.Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.Fetal serotonin reuptake inhibitor antidepressant exposure: maternal and fetal factors.Induction of cytochrome P450 enzymes: a view on human in vivo findings.Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction.Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.In vitro drug-drug interactions of budesonide: inhibition and induction of transporters and cytochrome P450 enzymes.Impact of Drug Treatment at Neonatal Ages on Variability of Drug Metabolism and Drug-drug Interactions in Adult Life.Expression and induction by dexamethasone of ABC transporters and nuclear receptors in a human T-lymphocyte cell line.
P2860
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P2860
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Dual effect of dexamethasone o ...... eptor and pregnane X receptor.
@en
type
label
Dual effect of dexamethasone o ...... eptor and pregnane X receptor.
@en
prefLabel
Dual effect of dexamethasone o ...... eptor and pregnane X receptor.
@en
P2093
P2860
P1433
P1476
Dual effect of dexamethasone o ...... ceptor and pregnane X receptor
@en
P2093
P2860
P304
P356
10.1046/J.0014-2956.2001.02540.X
P407
P577
2001-12-01T00:00:00Z