Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes
about
Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liverDeterminants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACIDFormation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective EffectsHepatobiliary disposition of troglitazone and metabolites in rat and human sandwich-cultured hepatocytes: use of Monte Carlo simulations to assess the impact of changes in biliary excretion on troglitazone sulfate accumulation.Pharmacogenetics of Anti-Diabetes Drugs.Expression pattern of human ATP-binding cassette transporters in skin.Cytochrome P450 2C8 pharmacogenetics: a review of clinical studiesThe effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects.The xenobiotic inhibitor profile of cytochrome P4502C8.Cytotoxicity of 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT) and analogues in wild type and CYP3A4 stably transfected HepG2 cells.Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liverBiological interactions of CYP2C19 genotypes with CYP3A4*18, CYP3A5*3, and MDR1-3435 in living donor liver transplantation recipients.PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8.Homogeneous phenomenon of the graft when using different genotype characteristic of recipients/donors in living donor liver transplantation.Comparison of hepatic 2D sandwich cultures and 3D spheroids for long-term toxicity applications: A multi-center study.
P2860
Q24304203-369316BA-200E-41FC-B7FC-C5E4F0C974E7Q27650327-D45A3BBC-BF7F-44DE-AD1F-07377B1A82C2Q28468284-CC800624-3598-47EE-8984-02D2E4236887Q33574904-92B72991-A29D-4092-B5A8-AF622656681EQ34181995-9E1B3CB2-62BA-488F-BB7D-5C75F5529F8EQ34286447-D1991E52-60F4-415F-AF30-F7D8A1096DDDQ35003605-D678B986-AC08-4A4E-88F5-ACD4C0E50F23Q35827277-66A85DB7-0B8E-4FFB-B631-EFC2186C1DEEQ36055384-7449E659-ED74-4E22-83D1-D14D5EF25278Q36067499-18B2EBD5-23F7-417D-AA9F-BACE85B2FB75Q36174736-F7D75FF6-0B37-4E96-AECB-10758143042AQ36814845-9589BD3F-6645-40B4-8010-CFE27C1BD5BAQ38130410-4DF40EC1-703E-4FC1-AD93-6A1E249A0FE7Q41918312-D6E39073-AE1B-4630-9A17-124AA2C7A087Q50062827-BAE39957-5959-4ADE-BC5A-E1C90DA78307
P2860
Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@ast
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@en
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@nl
type
label
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@ast
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@en
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@nl
prefLabel
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@ast
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@en
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@nl
P2093
P1476
Oxidation of troglitazone to a ...... 3A4 in human liver microsomes
@en
P2093
F P Guengerich
H Yamazaki
M Nakajima
P304
P407
P577
1999-11-01T00:00:00Z